近日,中南大学湘雅医院肿瘤科曾珊、韩莹、申竑教授团队在国际期刊Autophagy上发表了题为HMBOX1 reverses autophagy mediated 5-fluorouracil resistance through promoting HACE1-induced ubiquitination and degradation of ATG5 in colorectal cancer(...
近日,中南大学湘雅医院肿瘤科曾珊、韩莹、申竑教授团队在国际期刊Autophagy上发表了题为HMBOX1 reverses autophagy mediated 5-fluorouracil resistance through promoting HACE1-induced ubiquitination and degradation of ATG5 in colorectal cancer(HMBOX1通过促进HACE1诱导的ATG5泛素化降解逆转自噬介导的结直肠癌5-氟尿嘧啶...
autophagyBackground Accumulating studies demonstrated that resistance of colon cancer (CC) to 5-fluorouracil (5-FU) contributes to adverse prognosis. We investigated how Kruppel-like factor 4 (KLF4) affected 5-FU resistance and autophagy in CC cells. Methods KLF4 expression and its downstream target...
P62 and DPD in HCT-8 and HCT-8/5-FU cells;D:MDC method was used to detect the autophagy level of HCT-8 cells.E:MDC method was used to detect the autophagy level of HCT-8/5-FU cells.F:Incidence of autop...
[5] Focaccetti C, et al. Effects of 5-Fluorouracil on Morphology, Cell Cycle, Proliferation, Apoptosis, Autophagy and ROS Production in Endothelial Cells and Cardiomyocytes. PLoS ONE 10(2): e0115686 (2015). HB210826
Autophagy is essential for effector CD8(+) T cell survival and memory formation. Nat Immunol. 2014; 15:1152–1161. [PubMed: 25362489]会员登录 × 请输入账号 请输入密码 = 请输验证码 立即登录新用户注册收藏该商铺 X 该信息已收藏! 查看我的收藏夹设置标签 标签: 添加 保存成功 (空格分隔,最...
Effects of 5-fluorouracil on morphology, cell cycle, proliferation, apoptosis, autophagy and ROS production in endothelial cells and cardiomyocytes. PLoS One. 2015;10(2):e0115686. Article PubMed PubMed Central Google Scholar Spasojevic I, Maksimovic V, Zakrzewska J, Bacic G. Effects of 5-...
μg / mL. Autophagsomes and autophagy vesica were observed in CD133 + CSCs. The combination treatment of 5FU and 3MA significantly decreased the viability of CD133 + CSCs from ( 81. 8 ʃ 4. 6 ) % to ( 56. 3 ʃ 5. 5 ) % ( P < 0. 05 ), and the colonyforming ...
Schizandrin A can inhibit non-small cell lung cancer cell proliferation by inducing cell cycle arrest, apoptosis and autophagy. Int J Mol Med 2021;48:214. . Google Scholar L Zhu, Y Wang, W Lv, X Wu, H Sheng, C He Schizandrin A can inhibit non-small cell lung cancer cell ...
Schizandrin A can inhibit non-small cell lung cancer cell proliferation by inducing cell cycle arrest, apoptosis and autophagy. Int J Mol Med 2021;48:214. https://doi.org/10.3892/ijmm.2021.5047.Search in Google Scholar PubMed PubMed Central 10. Fu, K, Zhou, H, Wang, C, Gong, L, ...