Cellular repair: Fasting activates autophagy, a cellular repair process where the body clears out damaged cells, potentially reducing the risk of diseases and promoting longevity. (6) However, it’s important to note that the process of cellular repair seems to occur in many different calorie defi...
How to reduce the risk of failing to reach recruitment targets: lessons learnt from a pump pilot trialinsulin/IGF-1TORgermlineautophagylipid metabolismagingDiabet. Med. 29, 1600–1601 (2012)doi:10.1111/j.1464-5491.2012.03706.xBarnard, K. D....
I want there to be a great future for those of us who (like myself) want to become posthumans. I want to encourage all humans to explore enhancing their health, intelligence and productivity. There is a real risk of being left behind if you do not do that. I also want all of human...
That is a major diet question that has been debated for a number of years; and is a key component of autophagy. Many women swear by it, not only for weight control, but claim it also helps to achieve greater physical as well as mental efficiency. While eating absolutely nothing is very ...
Other forms of inflammatory cell death can occur in IECs; however, in this review we focus on the 3 main types of cell death specific to IECS: apoptosis, autophagy, and anoikis. Dysfunction of the Intestinal Barrier in IBD In the last 50 years, there has been an increase in the incidence...
damaged cellular components can cause age-related decline, if not removed from our system. It appears that CR boosts the process ofautophagy, an important catabolic process involving the degradation of a cell's own components, thus allowing the newly created cellular components to function properly....
The second way is calledautophagy, and it goes hand in hand with letting your body rest from digestion. Autophagy is the process that cells use to remove waste, including malfunctioning parts of cells, or even whole cells that are not functioning correctly and can’t be healed. If you have...
and present treatments and summarises mechanisms of resistance to targeted therapies and highlights new potential drug targets that have emerged in recent studies on metabolic effects, slow cycling tumour cells, phenotypic switching, as well as ER-stress, autophagy and miRNA-mediated resistance ...
Complex interrelated genetic, environmental and age-related factors determine an individual's vulnerability or resilience to inflammaging. These factors include polymorphisms to the promoter regions of cytokines, cytokine receptors and antagonists, age-related decreases in autophagy and increased adiposity. ...
- Gemella has been shown to reduce IL-12 levels in oral infections in mice [113]. Involvement in therapy • F. nucleatum promotes (chemo)resistance of CRC cells by triggering autophagy activation [52].• F. nucleatum reduces chemosensitivity in CRC cells through NF-κB, followed by ...