Acomelatine(阿戈美拉汀)是一种新型抗抑郁药物,它可以在晚上调节睡眠结构,改善睡眠质量,并在白天缓解兴趣减退、动力不足和愉悦感缺失等症状,具有独特的MT激动和5-HT2C受体拮抗作用,总体来说,其耐受性较好。 格宁生物相关实验 5-HT2C:IP-1检测 下图为HEK293 5-HT2C Gq细胞系,过度表达5-HT2C受体,用于检测在受体激动...
5-HTx agonist5-HT2C receptorAlzheimer's diseaseanxietydepressionepilepsyG-protein-coupled receptorhot flushesobesityWhile there is evidence for the involvement of different serotonin (5hydroxytryptamine; 5-HT) receptors in the regulation of food intake and body weight maintenance, the data supporting the...
5-HT2A receptor agonist-3,具有当前已知的最高选择性,是针对人类5-HT2A receptor的激动剂,其Ki值仅为2.5 nM。该化合物相较于结构类似的5-HT2A receptor激动剂,其对5-HT2A的选择性高达124倍。 规格价格库存数量 5 mg 询价 8-10周 50 mg 询价 8-10周 大包装 & 定制 加入购物车 TargetMol 的所有...
5-HT2A receptor agonist-2用途 5-HT2A受体激动剂-2是一种高效的5-HT2受体激动剂。5-HT2A受体激动剂-2分别以1.7、0.58和0.50 nM的EC50值激发5-HT2A、5-HT2B和5-HT2C[1]。 5-HT2A receptor agonist-2名称 英文名5-HT2A receptor agonist-2 ...
5HT2C receptor agonistPyrazinobenoxazinoneAnorecticObesitySubstituted 2,3,4,4a-tetrahydropyrazino[2,1-c][1,4]benzoxazin-5-(1H)-ones were synthesized and evaluated as 5-HT(2C) receptor agonists for the possible treatment of obesity. A number of compounds exhibited 5-HT(2C) agonist binding ...
Several 5-HT2C agonists are in development or on the market to treat not only food intake and obesity, but also various types of addiction, including smoking and possibly drug-related addictions. In addition, the antidepressant agomelatine is melatonin receptor agonist and 5-HT2C receptor antagonist...
www.nature.com/scientificreports OPEN Evaluation of a 5‑HT2B receptor agonist in a murine model of amyotrophic lateral sclerosis Alizée Arnoux1,2,3, Estelle Ayme‑Dietrich2, Stéphane Dieterle1, Marc‑Antoine Goy1, Stephan Schann3, Mélanie Frauli3, Laurent ...
5-羟色胺受体2C抗体(5HT2C Receptor) 价 格 ￥1680 起批量 ≥1支 最小起订1支 供货总量50支 发货地址浙江省温州市 建议售价￥1680/支 更新日期 2025年04月14日 产品规格100ul 即时洽谈 立即询价 查看联系方式 收藏产品 发送留言 举报 VIP3年 温州科淼生物科技有限公司 企业认证: 备 营业执照...
Advancements in precision medicine drive the 5-HT2 agonist market by enabling selective targeting of specific receptor subtypes (e.g., 5-HT2A or 5-HT2C), reducing side effects and improving safety. Personalized approach...
The present invention relates to processes and intermediates useful in the preparation of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine (lorcaserin), a serotonin (5-HT) receptor modulator that is useful in the treatment of, for example, central nervous system disorders, such ...