Serotonin (5-HT) and 5-HT2A receptor agonists suppress lipolysis in primary rat adipose cells. Biochem Biophys Res Commun 2016; 474(2): 357-363.Hansson, B., Medina, A., Fryklund, C., Fex, M., Stenkula, K.G., 2016. Serotonin (5- HT) and 5-HT2A receptor agonists suppress ...
5-HT receptor agonists and antagonists used for various assays, some have entered clinical trials, which would be new cancer therapies.
5-hydroxytryptamine receptor 5A (5-HT5A) belongs to the 5-HT receptor family and signals through the Gi/oprotein. It is involved in nervous system regulation and an attractive target for the treatment of psychosis, depression, schizophrenia, and neuropathic pain. 5-HT5Ais the only Gi/o-coupl...
5-HT 1A receptor agonists have been found to be effective in preventing toxin-induced apoptosis in primary hippocampal and cortical cultures [24,25], and in cultured neurons from chick embryo telencephalons [26]. These protective effects appear to derive from the ability of the receptor to ...
6. 血清素受体作用剂(Serotonin receptor agonists)。7. 其他药物:抗凝血剂、口服避孕药、抗组织氨剂、四环型抗生素、止…tw.myblog.yahoo.com|基于3个网页 2. 血清素受体激动剂 ...ents) 致幻药(Hallucinogens) 血清素受体激动剂(Serotonin Receptor Agonists) 苯丙胺(Amphetamine) new.med.wanfangdata.com.cn|...
The aim of the present study was to determine the 5-HT receptor subtypes involved in the serotonin-induced inhibition of L-leucine absorption across rabbit jejunum in vitro. A number of agonists and antagonists were used to characterize the receptors through which serotonin inhibits this absorption....
among the 5-HT receptors agonists tested, 2-methyl-5-HT (1-10 μM), a 5-HT3 receptor agonist, inhibited oxotremorine-, histamine- and pentagastrin-stimulated acid secretions, and this inhibitory effect was blocked by 1 μM MDL 72222, a specific 5-HT3 receptor antagonist. ...
In HEK293 cells, which are loosely adherent, expression and stimulation of human or rat 5-HT2Areceptor by agonists such as serotonin or 2,5-dimethoxy-4-iodoamphetamine (DOI) led to a significant increase in adhesion, while inhibition of 5-HT2Aby antipsychotics, such as risperidone, olanzapine...
LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex Correlations between 5-hydroxytryptamine (5-HT) receptor binding affinities and human hallucinogenic potency have suggested that 5-HT2 receptors mediate the hallucinogenic eff...
1. Structures of reference 5-HT1 receptor agonists. While there are no approved drugs that selectively target individual 5-HT1A, 5-HT1B, or 5-HT1D receptor subtypes, there are several commercially available pharmaceutical-like compounds that selectively activate 5-HT1A receptors. For example, 8-...