The 5-HT 2C receptor was one of the first receptors of the 5-HT family to be cloned; although full-length sequences were difficult to obtain, due to a complex exon-intron structure. The receptor was mapped to h
A variety of ligands binds to the serotonin 2A receptor (5-HT2A), including biogenic amines, synthetic hallucinogenic tryptamines, as well as the recreational drugs: psilocin, psilocybin, lysergic acid diethylamide (LSD), and the hallucinogens: 2,5-dimethoxy-4-iodoamphetamine (DOI) and 2,5-...
盐酸鲁拉西酮: 一种5-HT2A receptor拮抗剂、D2 receptor拮抗剂药物,由Sumitomo Pharma Co., Ltd. (Sumitomo Pharma Co., Ltd.)公司最早进行研发,目前全球最高研发状态为批准上市,作用机制: 5-HT2A receptor拮抗剂(5-羟色胺2A受体拮抗剂),D2 receptor拮抗剂(多巴胺D2受体
Ritanserin (R 55667) 是一种 5-HT2 受体拮抗剂。 产品性质 性质名称 性质详情 CAS 号(CAS NO.) 87051-43-2 英文别名(English Synonym) Ritanserin 中文名称(Chinese Name) 利坦丝林; 利坦色林 靶点(Target) 5-HT2 receptor H1 receptor D2 receptor α1 receptor α2 receptor ...
The serotonin (5-hydroxytryptamine, 5-HT) 5-HT2C receptor (5-HT2CR) within the medial prefrontal cortex (mPFC) is uniquely poised to serve as a strategic nexus to mechanistically control these behaviors. The 5-HT2CR functional capacity is regulated by a number of factors including availability...
TCB-2 is a high affinity 5-HTreceptor agonist (Kvalues are 0.73 and 0.75 nM for rat and human receptors respectively). Potently stimulates IPaccumulation in NIH3T3 cells stably expressing rat 5-HTreceptors (EC= 36 nM). Induces head twitches and hypothermia in mice following i.p. administrat...
5-HT2拮抗剂1用途 5-HT2 antagonist 1 是一种有效的 5-HT2 receptor 拮抗剂,同时对 α1 adrenoceptor 有微弱地抑制作用。 产品性质 图谱目录: 名称 生物活性 物理化学性质 英文别名 返回顶部 5-HT2拮抗剂1名称 中文名 5-HT2拮抗剂1 英文名 5-HT2 antagonist 1 英文别名 更多 ...
SB 204741 has been used as a 5-hydroxytryptamine receptor 2B (Htr2B) antagonist: to inhibit Htr2b signaling to test its effect on hepatic stellate cell (HSC) activation in three-month-old adult zebrafish to test its effect on the inhibition of fluoxetine effects in depressive-like behavioral ...
Iloperidone(HP 873; HP873;伊潘立酮)是一种D2/5-HT2受体拮抗剂(dopamine/serotonin receptor抑制剂,多巴胺/血清素受体拮抗剂),也是非典型性抗精神病药,对5-HT2A受体的亲和力(Ki<10 nM)高于D2受体(Ki=10-100 nM),可治疗精神上的情绪类的疾病。
The 5-HT2A receptor agonists such as mCPP have been shown to decrease learning and memory in rats (Meneses, 1999). The same mechanism might be responsible for the decrement in learning and delayed recall following MDMA administra- tion, as it has been previously demonstrated that MDMA ...