& CAMPBELL, I.C. (1988). Circadian studies of 5HT2 receptors: effects of clorgyline administration. Pharmacol. Biochem. Behav. (in press).Koshikawa, N., Durcan, M. J., Dunn, G., & Campbell, I. C. (1988). Circadian studies of 5HT2 receptors: Effects of clorgyline administration. ...
Serotonin (5-hydroxytryptamine, 5HT) was first discovered as a serum factor and later shown also to be a neurotransmitter in the central and peripheral nervous systems (reviewed by Leysen, 1988). It interacts with a family of pharmacologically distinct receptors on the surface of neurons and ...
Clinical Neuropharmacology: 1992 - Volume 15 - Issue Part B - ppg 54B Articles: PDF Only Postmortem Brain 5Ht2 Receptors in Schizophrenia: Effect of Neuroleptics and Suicide Pandey, G. N.; Conley, R. R.; Pandey, S. C.; Tamminga, C.; Peretti, F.; Davis, J. M.Logi...
Chronic treatment of rats with the antidepressant, amitriptyline, resulted in a reduced number of cerebral cortical 5HT2 receptors measured as cinanserin displaceable [3H] spiperone binding. Pretreatment of rats with the serotonergic neurotoxin, p-chloroamphetamine, did not inhibit the effects of subse...
Serotonergic activation of 5HT(sub)1A( sub) and 5HT(sub)2( sub) receptors modulates sexually dimorphic communication signals in the weakly electric fish Apteronotus leptorhynchus 文档格式: .pdf 文档大小: 1.32M 文档页数: 14页 顶/踩数: ...
An in vivo receptor binding technique was used to evaluate the binding profiles of typical and atypical antipsychotic drugs to striatal dopamine-D 2 and frontal serotonin-5-HT 2 receptors in a rat brain using more specific ligands than those previously employed. [ 3 H]-YM-09151-2 or [ 3 ...
Disclosed herein are non-endogenous, constitutively activated forms of the human 5-HT.sub.2A and human 5-HT.sub.2C receptors and uses of such receptors to screen candidate compounds. Further disclosed herein are candidate compounds ident... DP Behan,DT Chalmers,NRA Beeley,... - CA 被引量:...
Cellular localization of serotonin(2A) (5HT(2A)) receptors in the rat brain. The serotonin2A (5HT2A) receptors have been shown to play an important role in several psychiatric disorders, including depression, schizophrenia, and alco...
Method of blocking 5HT.sub.2 without effect on alpha receptors with 1- loweralkyl-6-methyl-8&bgr;-(hydroxy)alkoxy carbonyl-5R-ergolines. Marlene L. Cohen,Ray W. Fuller 被引量: 16发表: 1986年 Indole derivatives as 5HT.sub.1 -like agonists Compounds of formula (I), pharmaceutically accept...
This invention provides (8β)-N-heteroalkyl-1-alkyl-6-(substituted)ergoline-8-carboxamides useful for blocking 5HT2 receptors in mammals having an excess of serotonin centrally or peripherally. The invention also provides methods for treating sexual dysfunction, hypertension, migraine, vasospasm, throm...