alpha-Phenyl-tert-N-butyl nitrone (PBN), a potent reactive oxygen species (ROS) scavenger, has shown robust neuroprotective properties in several models of acute brain injury, although not previously evaluated in traumatic brain injury (TBI). In this study, we assessed the potential efficacy of ...
transplant (BMT) model, in which administration of anti-CD40 antibody early after BMT results in overproduction of interleukin-12 (IL-12) and interferon-gamma (IFN-gamma), and lethal gut toxicity to examine the protective effect of the spin trap inhibitor, alpha phenyl-tert-butyl nitrone (PBN...
别名N-叔丁基苯硝酮 英文别名PBN | Phenyl-N-tert-butylnitrone | F0001-0991 | 2-Propanamine, 2-methyl-N-(phenylmethylene)-, N-oxide, (N(Z))- | N-tert-Butyl-.alpha.-phenylnitrone | (Z)-N-Benzylidene-2-methylpropan-2-amine oxide | n-tert-butyl phenyl nitrone | (Z)-benzylidene(ter...
中文别名:N-叔丁基-а-苯基硝酮 英文名称:N-tert-Butyl-Alpha-phenylnitrone 英文别名:PBN; Phenyl N-tert-butylnitrone; N-tert-Butyl-alpha-phenyl nitrone; Butylphenylnitrone; N-benzyliden-tert-butylamine N-ether; N-benzylidene-N-tert-butylamine oxide ...
摘要: Compounds derived from α-C-phenyl-N-tert-butylnitrone, a process for the preparation thereof and use thereof for the preparation of medicaments for use in preventing or treating oxidative stress-related diseases.收藏 引用 批量引用 报错 分享 文库来源 其他来源 求助全文 NOVEL AMPHIPHILIC ...
Product Name:N-TERT-BUTYL-ALPHA-PHENYLNITRONE Synonyms:c-phenyl-n-tert-butylnitrone;n-benzylidene-tert-butylamineoxide;n-tert-butyl-2-phenylnitrone;n-tert-butyl-alpha-phenyl-nitron;n-tert-butyl-c-phenylnitrone;(Z)-N-benzylidene-2-Methylpropan-2-aMine oxide;PHENYL N-TERT-BUTYLNITRONE;PBN ...
The aim of the present study was to investigate the involvement of HO-1, a heat shock/stress protein, in protection offered by the spin trap agent, N-tert-butyl-alpha-phenyl-nitrone (PBN), against kidney ischemia/reperfusion injury. For this, HO-1 expression and assessment of the ...
摘要: Novel pharmaceutical formulations of α-(2,4-disulfophenyl)-N-tert-butylnitrone and pharmaceutically acceptable salts thereof and the use of such formulations in the treatment of various diseases and conditions, especially stroke, are disclosed....
英文名称:N-TERT-BUTYL-ALPHA-(4-NITROPHENYL)NITRONE 英文同义词:N-TERT-BUTYL-ALPHA-(4-NITROPHENYL)NITRONE;n-tert-butyl-α-(4-nitrophenyl)nitrone;2-Methyl-N-[(4-nitrophenyl)methylene]-2-propanamineN-oxide;N-(4-Nitrobenzylidene)-1,1-dimethylethanamine N-oxide;N-(4-Nitrobenzylidene)-tert-buty...
In the first step, addition of methylmagnesium iodide to N-(phenylsulfonyI)-l-allothreonine afforded the α-amino methyl ketone in modest yield.59 This reaction afforded a diminished yield compared with N-(phenylsulfonyl)-l-threonine for some unexplained reason. A clever use of the l-amino ...