Ho E, Chen G, Bray TM (2000):Alpha-phenyl-tert- butylnitrone (PBN) inhibits NFkappaBactivation offering protection against chemically induced diabetes. Free Radic Biol Med.28(4):604-14.Ho E,Chen G,Bray TM.Alpha-phenyl-tert-butylnitrone (PB N) inhibits NF-κB activation offering protection...
别名N-叔丁基苯硝酮 英文别名PBN | Phenyl-N-tert-butylnitrone | F0001-0991 | 2-Propanamine, 2-methyl-N-(phenylmethylene)-, N-oxide, (N(Z))- | N-tert-Butyl-.alpha.-phenylnitrone | (Z)-N-Benzylidene-2-methylpropan-2-amine oxide | n-tert-butyl phenyl nitrone | (Z)-benzylidene(ter...
alpha-Phenyl-tert-N-butyl nitrone (PBN), a potent reactive oxygen species (ROS) scavenger, has shown robust neuroprotective properties in several models of acute brain injury, although not previously evaluated in traumatic brain injury (TBI). In this study, we assessed the potential efficacy of ...
This chapter describes the spin-trapping agent 伪-phenyl N-tert-butylnitrone (PBN) that offers protection by trapping free radicals during ischemia-reperfusion-mediated injury to the heart and brain of experimental animals. Thus, it has been of considerable interest to establish whether it also ...
Donepezil, tacrine and alpha-phenyl-n- tert-butyl nitrone (PBN) inhibit choline transport by conditionally immor- talized rat brain capillary endothelial cell lines (TR-BBB). Arch Pharma- col Res (Seoul) 28: 443- 450, 2005.Kang YS, Lee KE, Lee NY, et al. Donepezil, tacrine and alpha...
and PBN伪-phenyl-tert-butyl-nitrone (PBN) a spin adduct forming agent is believed to have a protective action in ischemia-reperfusion injury of brain by forming adducts of oxygen free radicals including 卤OH radical. Electron paramagnetic resonance (EPR) has been used to both detect and monitor...
(1996) alpha-Phenyl-N-tert-butyl nitrone attenuates methamphet- amine-induced depletion of striatal dopamine without altering hyperthermia. Synapse 24, 173-181.Cappon G. D., Broening H. W., Pu C., Morford L., Vorhees C. V. alpha-Phenyl-N-tert-butyl nitrone attenuates methamphetamine-...
It has previously been suggested that the spin trap agent 伪-phenyl-N-tert-butylnitrone (PBN) induces neurite outgrowth through activation of the Ras-ERK pathway in PC12 cells. However, the chemical properties of PBN contributing to its biological function and the detailed mechanism for the ...
Alpha(alpha)-Phenyl-N-tert-butylnitrone (PBN) is an antioxidant used to combat oxidative stress and measure increases in PBN spin-adduct activity. Thus, the aim of this study was to investigate whether VCMs are related to upregulation of DA-D2 receptors or to increased levels of free ...
(1995) The spin-trap N-tert-alpha-phenyl- butylnitrone prolongs the life span o f the senescence accelerated mouse. Biochem Biophys Res Commun 211, 847-849.Edamatsu R, A Mori & L Packer: The spin-trap N- tert-alpha-phenyl-butylnitrone prolongs the life span ...