Personalized cancer treatment and the myth of KRAS wild-type colon tumors. Discov. Med. 15 (83), 259-267.Parsons B L,Myers M B.Personalized cancer treatment and the myth of KRAS wild-type colon tumors[J].Discov Med,2013,15(83):259-267....
Chemotherapy for KRAS Wild-Type Colorectal Cancer JAMA Original Investigation June 20, 2017 This randomized clinical trial compares the effect of adding bevacizumab vs cetuximab to standard chemotherapy regimens on overall survival among patients with advanced or metastatic KRAS wild-type colorectal cancer....
Impact of subsequent therapies on outcome of the FIRE-3/AIO KRK0306 trial: first-line therapy with FOLFIRI plus cetuximab or bevacizumab in patients with KRAS wild-type tumors in metastatic colorectal cancer. J Clin Oncol. 2015;33(32):3718-3726.PubMedGoogle ScholarCrossref 19. Venook AP, ...
While many genome sequences are complete, transcriptomes are less well characterized. We used both genome-scale tiling arrays and massively parallel sequencing to map the Caenorhabditis elegans transcriptome across development. We utilized this framework
population, we estimate that these fish have FWT of 0 °C, meaning that they currently experience temperatures at the edge of their functional thermal limits. More temperature data will be required to determine if Arroyo Seco will consistently reach or exceed 23 °C in future years....
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(Krasovskaya and Levichev1986; Pratov et al.2006) and therefore may survive better in a changing landscape than our models predict. Although changes in climate may decouple seasonal triggers such as flowering time (Wadgymar et al.2018) which could be exceptionally damaging for tulips and ...
Impact of subsequent therapies on outcome of the FIRE-3/AIO KRK0306 trial: first-line therapy with FOLFIRI plus cetuximab or bevacizumab in patients with KRAS wild-type tumors in metastatic colorectal cancer. J Clin Oncol. 2015;33(32):3718-3726.PubMedGoogle ScholarCrossref 19. Venook AP, ...
Phase 2 study of irinotecan plus cetuximab rechallenge as third-line treatment in KRAS wild-type metastatic colorectal cancer: JACCRO CC-08. Br J Cancer. 2020;123(10):1490-1495. doi:10.1038/s41416-020-01042-wPubMedGoogle ScholarCrossref 21. Cunningham D, Humblet Y, Siena S...
Bailey HC, Krassoi R, Elphick JR, Mulhall AM, Hunt P, Tedmanson L, Lovell A (2000) Whole effluent toxicity of sewage treatment plants in the Hawkesbury-Nepean watershed, New South Wales, Australia, to Ceriodaphnia dubia and Selenastrum capricornutum. Environ Toxicol Chem 19:72–81 CAS Google...