Please see application and tech notes for additional guidance. Costs are estimates based on list prices. Please check with manufacturer for latest pricing or quote. Whole genome sequencing in action Case Study Pioneering a pangenome reference collection Learn about DuPont Pioneer’s ambitious ...
sectioned by a cryostat, and stained with hematoxylin and eosin. We performed macrodissection to enrich the tumor fraction relative to the dominant stromal component and other normal cells. DNA was extracted using a general protocol for genome sequencing. Preparation of ...
Ranging from 98.85 to 99.58% base pairs were totally mapped and aligned on the human reference genome GRCh37 hg19. Het/Hom and Ts/Tv ratios for each whole genome ranged from 1.35 to 1.49 and from 2.07 to 2.08, respectively. Sequencing data are available in the National Center for ...
Single-nucleotide variants (SNVs) associated with Parkinson’s disease (PD) have been investigated mainly through genome-wide association studies. However, other genomic alterations, including copy number variations, remain less explored. In this study, we conducted whole-genome sequencing of primary (...
Genetic factors modifying the blood metabolome have been investigated through genome-wide association studies (GWAS) of common genetic variants and through exome sequencing. We conducted a whole-genome sequencing study of common, low-frequency and rare variants to associate genetic variations with blood...
phylogenetic relationships and signature selections of Guizhou indigenous chicken breeds using SNPs generated from whole-genome re-sequencing. Meanwhile, the genomic data of two commercial chicken breeds and wild RJF were also included in the analysis of this study, aiming to identify potential candidate...
Carcinogens commonly leave imprints in the DNA. Thus, signatures of genomic events such as mutational signatures (MSs) are widely used in cancer etiological studies7,8,9. Whole-genome sequencing (WGS) is a powerful technology for investigations of alterations in intronic and intergenic regions as ...
Author notes Ming Liu, Caixia Yu, Zhichao Zhang and Mingjing Song contributed equally to this work. Authors and Affiliations State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China Ming Liu, Guoliang Li, Xinru Wan...
Rosacea is a chronic inflammatory skin disorder with high incidence rate. Although genetic predisposition to rosacea is suggested by existing evidence, the genetic basis remains largely unknown. Here we present the integrated results of whole genome sequ
(R. tarandus tarandus) from Sodankylä, Finland. In the present study, we improved the genome assembly of this same individual. The DNA for library preparations and sequencing was extracted using a standard phenol–chloroform extraction from liver and muscle samples, which were collected at ...