Whole-genome sequencing delivers a comprehensive view, ideal for discovery applications. Newer genome sequencers perform WGS more rapidly than ever.
Whole genome sequencing (WGS) of Mycobacterium tuberculosis has rapidly progressed from a research tool to a clinical application for the diagnosis and management of tuberculosis and in public health surveillance. This development has been facilitated by drastic drops in cost, advances in technology and...
《Laboratoriumsmedizin-journal of Laboratory Medicine》Klein HG, Bauer P, Hambuch T. Whole genome sequencing (WGS), whole exome sequencing (WES) and clinical exome sequencing (CES) in patient care. LaboratoriumsMedizin-Journal of Laboratory Medicine. 2014;38:221-30....
Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program The American Journal of Human Genetics, Volume 108, Issue 6, 3 June 2021, Pages 1165 Yao Hu, Adrienne M. Stilp, Caitlin P. McHugh, Shuquan Rao, Deepti Jain, Xiuwen Zheng, John...
et al. Whole-genome sequencing of giant pandas provides insights into demographic history and local adaptation. Nat Genet 45, 67–71 (2013). https://doi.org/10.1038/ng.2494 Download citation Received13 March 2012 Accepted14 November 2012 Published16 December 2012 Issue DateJanuary 2013 DOIhttps:...
Human population genomic studies, including whole‐genome sequencing, were undertaken to identify determinants of bone mineral density (BMD), a major predictor of osteoporotic fractures. Non‐coding variants with large effects on BMD and fractures were i
We acknowledge that obtaining fully informed consent for whole genome sequencing will always be a challenge since one cannot predict all the possible diagnoses or the incidental findings generated. However, we suggest that a time pause is allowed for patients to read the consent form and discuss it...
Amalio Telenti, Craig Venter and colleagues report common, low-frequency and rare variants associated with blood metabolite levels using whole-genome sequencing and comprehensive metabolite profiling in 1,960 individuals. They identify 246 metabolites wh
Sequencing. The bioinformatics workflow for WGS falls into the following steps: (1) raw read quality control; (2) data preprocessing; (3) alignment; (4) variant calling; (5)genome assembly; (6)genome annotation; (7) other advanced analyses based on your research interest such as phylogenetic...
GCAT genesT A C G GCAT Review The Present and Future of Whole Genome Sequencing (WGS) and Whole Metagenome Sequencing (WMS) for Surveillance of Antimicrobial Resistant Microorganisms and Antimicrobial Resistance Genes across the Food Chain Elena A. Oniciuc 1,†, Eleni L...