Metagenomics and Whole Genome Sequencing in Clinical Microbiology: A Narrative Reviewdoi:10.7860/JCDR/2023/65580.18779MEDICAL microbiologyWHOLE genome sequencingDETECTION of microorganismsMETAGENOMICSCOMMUNICABLE diseasesMOLECULAR epidemiologyThe role of Whole Genome Sequencing (WGS) in cl...
Mycobacterium tuberculosis and whole-genome sequencing: how close are we to unleashing its full potential? Clin. Microbiol. Infect. 24, 604–609 (2018).An extensive review of the literature outlining the potential of WGS for TB research and clinical use. CAS PubMed Google Scholar Lipworth, S...
The whole-genome resequencing data was generated for the samples from 36 wild mice by Illumina technology. Approximately 1.4 Tb data was acquired. Raw sequencing data for the 36 wild mice ranged from 24.4 to 54.3 Gb (Additional file1: Table S3). After mapping to the mouse reference genome (...
Whole-genome sequencing (WGS) is widely employed to diagnose rare [31,32,33,34,35] and undiagnosed diseases [36] and identify actionable cancer drivers and signatures. The different clinical applications and the type of analyses that are implicated in the diagnostics are shown in Fig.2. There ...
Carcinogens commonly leave imprints in the DNA. Thus, signatures of genomic events such as mutational signatures (MSs) are widely used in cancer etiological studies7,8,9. Whole-genome sequencing (WGS) is a powerful technology for investigations of alterations in intronic and intergenic regions as ...
These published genome sequences were investigated in this review, covering their classification, research teams, ploidy, medicinal functions, and sequencing strategies. More than 1,000 institutes or universities around the world and 50 countries are conducting research on medicinal plant genomes. Diploid...
Whole-genome sequencing reveals untapped genetic potential in Africa's indigenous cereal crop sorghum 来自 万方 喜欢 0 阅读量: 333 摘要: Sorghum is a food and feed cereal crop adapted to heat and drought and a staple for 500 million of the world's poorest people. Its small diploid genome ...
Physician review of sequencing findings prompted consideration of a median of 1 to 3 initial diagnostic tests and referrals per participant, with fair interrater agreement about the suitability of WGS findings for clinical follow-up (Fleiss κ, 0.24; P<001). CONCLUSIONS AND RELEVANCE: In this ...
Genome Editing for Rare Diseases Purpose of the Review Significant numbers of patients worldwide are affected by various rare diseases, but the effective treatment options to these individ... A Pradhan,TV Kalin,VV Kalinichenko - 《Current Stem Cell Reports》 被引量: 0发表: 2020年 Here we intr...
not differ between PD batches 1 and 2 (Wilcoxon-rank sum test).fInterval between blood sampling and time of onset of PD.gAge distribution of healthy individuals at the time of blood sampling. CNV copy number variation; HC healthy control; PD Parkinson’s disease; WGS whole-genome sequencing....