Whole genome sequencing (WGS) is the comprehensive read and analysis of an entire genome, including non-coding regions of the genome.
Use microbial whole-genome sequencing to map genomes of novel organisms, finish genomes of known organisms, or compare genomes across multiple samples.
(bacteria-infectingviruses) MS2 and ΦX174, which have relatively small genomes. Since then there have been numerousinnovationsin the field ofDNA sequencingthat have expanded the capabilities of thetechnology. Those innovations, combined with increasing cost-effectiveness in the early 21st century, ...
Whole genome sequencing can quickly isolate the specific strain of bacteria causing an outbreak, identify the source of contamination, and enable rapid infection prevention to stop the spread of infection, according to a study published today. The findings, based on the examination of an outbreak ...
Whole genome sequencing (WGS) of Mycobacterium tuberculosis has rapidly progressed from a research tool to a clinical application for the diagnosis and management of tuberculosis and in public health surveillance. This development has been facilitated by drastic drops in cost, advances in technology and...
In this regard traditional whole-genome sequencing methods and analysis which worked well for drug-resistant bacteria spread mainly by clonal transmission, for example MRSA21, would need to be augmented by robust plasmid linkage methods for CPE transmission. Our findings in the context of a national...
Attention was particularly drawn to a potentially new or novel Corynebacterium species which had the smallest genome, and which produced a range of hydrolytic enzymes. Strikingly the isolate inhibited in vitro the growth of a range of possible pathogenic bacteria as well as other Corynebacterium ...
Keywords: Carbapenem-resistant Klebsiella pneumoniae, Whole-genome sequencing, Bacteria epidemiology Background Klebsiella pneumoniae bacteria are normal gastrointestinal flora but, particularly in people with weakened immune systems and/or debilitating diseases, can also cause severe infections whose management ...
Microbial prospection of an Amazonian blackwater lake and whole-genome sequencing of bacteria capable of polyhydroxyalkanoate synthesisBiopolymers are driving the plastic industry to the next generation of environmentally friendly bioproducts, considering green chemistry principles and contemporary economic ...
Complete genome sequences of several pathogenic bacteria have recently been determined. Even though microbial genomics has had little direct impact on antibacterial drug discovery so far, the pos- sibilities of using complete genome sequences for target identifica- tion are virtually unlimited33. In ...