To explore the origins of the Lake Malawi radiation in greater detail, we obtained 24 additionalAstatotilapiawhole-genome sequences from outside Lake Malawi: fiveA. callipterafrom Indian Ocean catchments, thus covering most of its geographical distribution, and 19 individuals from seven otherAstato...
Low-Pass Whole Genome Sequencing Accurately detect genetic variation throughout genomes of a multitude of species. Achieve up to 99% accuracy of variant call detection at a very low sequence coverage (0.1X<10X) using imputation algorithms.
Nik-Zainal, S., et al., Landscape of somatic mutations in 560 breast cancer whole-genome sequences. Nature, 2016. 534(7605): p. 47-54. 研究人员测了560位乳腺癌患者(556位女性和4位男性)的肿瘤和正常组织的全基因组,共鉴定出93个驱动基因,以及与缺陷DNA修复和BRCA1及BRCA2功能相关的突变标签(mut...
Whole-genome sequencing delivers a comprehensive view, ideal for discovery applications. Newer genome sequencers perform WGS more rapidly than ever.
1) whole genome sequence 全长基因组序列2) complete nucleotide sequence 基因组全序列 1. The complete nucleotide sequence of an isolate of LMV from Yuhang was determined. 测定了莴苣花叶病毒 (LMV)浙江余杭分离物基因组全序列。 更多例句>> 3) complete geneome DNA sequence 基因组DNA全序列...
et al. Whole-genome sequencing and social-network analysis of a tuberculosis outbreak. N. Engl. J. Med. 364, 730–739 (2011). CAS PubMed Google Scholar Cole, S. T. et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393, 537–544 (...
In comparison to targeted sequencing that is often limited to a subset of genes of interest, WGS includes coverage of all coding and non-coding regions, regulatory sequences, and inter- and intra-genic portions of the genome. Then, the sequencing data are aligned to a reference genome for ...
72 °C for 1 min) × 35 cycles, 72 °C for 10 min. The PCR products were identified using 1.5%agarose gel electrophoresisand then sent to Sangon Biotech (Shanghai, China) forSanger sequencing. Finally, the complete genome sequences of two isolates (A/QH/219/2017 and A...
Developing and characterising Ricinus communis SSR markers by data mining of whole-genome sequences. Mol. Breed. 34, 893-904.Tan ML, Wu K, Wang L, Yan MF, Zhao ZD, Xu J, Zeng Y, Zhang XK, Fu CL, Xue JF, Wang LJ, Yan XC (2014) Developing and characterising Ricinus communis SSR ...
The Introduction of Whole Genome Sequencing Whole genome sequencing represents the determination of the complete DNA sequence of an organism's genome at a single time, which entails chromosomal DNA as well as DNA contained in mitochondria and chloroplasts. Whole genome sequencing provides a powerful to...