The mtDNA phylogeny is an outlier, substantially different from all the whole-genome phylogenies and also from the majority of the local maximum likelihood trees (Fig.2b,cand Supplementary Figs.6and11). Discordances between mtDNA and nuclear phylogenies in Lake Malawi have been reported previously a...
an entire human genome can be sequenced within 2 days at the price of a few hundred dollars. The relatively modest costs per analysis, combined with excellent data quality [10], make whole genome sequencing (WGS) a valuable source of information in many clinical situations. Compared ...
We sequenced the S. haematobium genome from 200 ng of genomic DNA template isolated from a single, mated pair (one male and one female) of adult worms, and produced 33.5 Gb of usable sequence data (Supplementary Note, Supplementary Tables 1–3, Supplementary Figs. 1 and 2). We consistentl...
CHANGCHUN, June 3 (Xinhua) -- Chinese scientists have sequenced the whole genome of 3,800-year-old wheat seeds unearthed from Xinjiang Uygur Autonomous Region, decoding the food crop's spreading route into China. Four Chinese institutes jointly conducted the research. The scientists extracted DNA ...
The whole-genome resequencing data yielded 17,295,344 SNPs across the 11 wildM. m. domesticussamples (Additional file1: Table S4). Totally, 143,421 SNPs were distributed in exons, 3,997,285 in introns, and 9,949,066 in intergenic regions. The genome resequencing analysis from 9 wildM. ...
An important approach used by many projects that sequenced large genomes involvedhierarchical shotgun sequencing, in which segments of genomic DNA were cloned (copied) and arranged into ordered arrays. Those ordered arrays were known as physical maps, and they served to break large genomes into thou...
To better understand the evolution of sex chromosomes and the plasticity of sex-determination mechanisms, we sequenced the whole genomes of a male (ZZ) and a female (ZW) half-smooth tongue sole (Cynoglossus semilaevis). In addition to insights into adaptation to a benthic lifestyle, we find ...
Whole genome sequenced Campylobacter isolates comprising 500 clinical isolates from human patients and 673 isolates from five food and animal sources were obtained : cattle (150), chicken (150), pig (130), sheep (150) and wild bird (93) (Suppl data file S1). PanSeq79 was used to construct...
(Supplementary Table7). We sought further replication for rs3215707 from additional independent samples. We interrogated 233 individuals from families with dyslipidemia and enriched for premature coronary heart disease who were whole-genome sequenced within the EUFAM study8. Using a mixed model, ...
We sequenced the whole genomes of 34 pandas at an average 4.7-fold coverage and used this data set together with the previously deep-sequenced panda genome(4) to reconstruct a continuous demographic history of pandas from their origin to the present. We identify two population expansions, two ...