In addition, a similarly significant decrease by 66% was shown for the SGLT-2 inhibitor/GLP-1RA combination compared to SGLT-2 inhibitor/placebo combination (RR = 0.34, 95% CI; 0.15 - 0.76, I2 = 0%).Conclusions: SGLT-2 inhibitor/GLP-1RA combination is not superior to SGLT-2 inhibit...
The rates of depression were similar for the GLP-1RA group and sodium-glucose cotransporter-2 inhibitor (SGLT2i) group. However, compared to participants taking dipeptidyl peptidase-4 inhibitors (DPP4is), GLP-1RAs were associated with a slight decrease in depression risk. This research adds more...
Using datasets from the United States, Germany, Spain, and the United Kingdom, Khera and his team compared how well each of the four different second-line diabetes medication classes reduced adverse cardiovascular events, including heart attack, stroke, and death, among type 2 diabetes patients w...