However, the risk is also relatively high, as there is a possibility of activating the systemic non-specific immune response, and in severe cases, cytokine storms can be life-threatening. 2. The ISAC components 2.1. Antibodies in the ISAC Antibodies serve as targeted agents in ISAC. The ...
In one study, microarray profiling demonstrates that while DEX can decrease human monocyte expression of many anti-inflammatory genes, it simultaneously increases the expression of a number of proinflammatory chemokines, complement proteins, and cytokines (Galon et al., 2002). An essential component of...
To express all its genes, HIV produces a large number of differentially spliced transcripts collectively termed “cell-associated (CA) HIV RNA” [1,2]. In HIV-infected individuals, especially those on suppressive antiretroviral therapy (ART), CA HIV RNA is an important surrogate marker of the v...
To express all its genes, HIV produces a large number of differentially spliced transcripts collectively termed “cell-associated (CA) HIV RNA” [1,2]. In HIV-infected individuals, especially those on suppressive antiretroviral therapy (ART), CA HIV RNA is an important surrogate marker of the v...