However, the risk is also relatively high, as there is a possibility of activating the systemic non-specific immune response, and in severe cases, cytokine storms can be life-threatening. 2. The ISAC components 2.1. Antibodies in the ISAC Antibodies serve as targeted agents in ISAC. The ...
As the HDL particle lipidates itself by delipidating the macrophage (i.e., takes lipid out of the foam cell), the HDL particle, utilizing an enzyme called LCAT, esterifies the free cholesterol forming cholesteryl ester (CE). As a result, the HDL particle enlarges and is free to be d...
To express all its genes, HIV produces a large number of differentially spliced transcripts collectively termed “cell-associated (CA) HIV RNA” [1,2]. In HIV-infected individuals, especially those on suppressive antiretroviral therapy (ART), CA HIV RNA is an important surrogate marker of the v...
To express all its genes, HIV produces a large number of differentially spliced transcripts collectively termed “cell-associated (CA) HIV RNA” [1,2]. In HIV-infected individuals, especially those on suppressive antiretroviral therapy (ART), CA HIV RNA is an important surrogate marker of the v...
Finally, in monocyte-derived osteoclasts, Hck was found to accumulate at podosome belts. In conclusion, in monocyte-derived cells, it is likely that Hck could play a role in podosome re-arrangements. 展开 关键词: Podosome Macrophage Osteoclast Chronic myeloid leukemia Hck Src Actin ...
As mentioned in the first section of the results in this study, the unitary-MI product IL-6 (4 CH) could activate the monocyte/macrophage sub-population and specifically increase the expression of CD69. To further investigate the role of the tested item on macrophages, we then checked its ...
(MR). Results: SM50 increased levels of all chemokines analyzed and TNF production, while it presented an increased inflammatory cell infiltrate in the skin with macrophage recruitment. Thus, we proposed a vaccine candidate employingL.(V.)braziliensisantigen associated with the SM adjuvant system ...