The meaning of MACROPHAGE is a phagocytic tissue cell of the immune system that may be fixed or freely motile, is derived from a monocyte, functions in the destruction of foreign antigens (such as bacteria and viruses), and serves as an antigen-presentin
Among them are several genes well known to be related with differentiation process as well as monocyte and macrophage functions. This involves proteins known to be involved in the differentiation process (CDK inhibitor p21), cytokine transporter like A2M, chemokines like CCL3 and IP10 as well as...
Monocyte/macrophage recruitment and expression of endothelial adhesion proteins in human atherosclerotic lesions. Atheroscle- rosis. 1996;121:253-266.Duplaa C,Couffinal T,Labat L,et al.Monocyte/macrophage recruitment and expression of endothelial adhesion proteins in human atherosclerotic lesilns. ...
(1998) Difference in the blood monocyte phenotype between uremic patients and healthy controls: its relation to monocyte differentiation into macrophage in the... A Brauner,L Ying,G Halldén,... - 《Inflammation》 被引量: 64发表: 1998年 ...
Brain macrophages include microglia in the parenchyma, border-associated macrophages in the meningeal-choroid plexus-perivascular space, and monocyte-derived macrophages that infiltrate the brain under various disease conditions. The vast heterogeneity of these cells has been elucidated over the last decade...
These data indicate a dichotomous nature of LF binding on monocyte/macrophage-differentiated HL-60 cells--one being mediated by specific LF receptors whereas the other is apparently mainly via LPS receptors after formation of an LF-LPS complex. These interactions, for which a model is proposed, ...
Assays of K562 and macrophage cell supernatants confirmed that the ferric reductase activity was not due to a secreted factor. Assay of ferric reductase in normalized-iron and iron-enriched (100 microM ferric citrate) conditions showed no significant difference between Cys282Tyr (Cys282-->Tyr) ...
To investigate the nuclear mechanics in monocyte differentiation, we treated bone marrow-derived monocytes with GM-CSF and M-CSF, respectively. Similar to the case of M1-M2 polarization, the size of the M1-like nucleus was found to be significantly smaller than that of the M2-like nucleus ...
G. Monocyte recruitment during infection and inflammation. Nat. Rev. Immunol. 11, 762–774 (2011). CAS PubMed PubMed Central Google Scholar Gibbings, S. L. et al. Transcriptome analysis highlights the conserved difference between embryonic and postnatal-derived alveolar macrophages. Blood 126, ...
To understand further the activation characteristics of SS-TAM data sets, we analyzed the transcriptomic profiles of a range of monocyte and macrophage data sets selected from the Gene Expression Omnibus (GEO) data repository. Suitable data sets were used to construct the large networks shown inFigu...