What are the initiator caspases in apoptosis signaling pathways? Where does detoxification occur in the cell? When does cell differentiation occur? Where does deamination occur in the cell? When a stimulus acts on a neuron it When do catabolic reactions take place?
In how many of the integers between 1 and100 does the digit 5 occur exactly once? If x,Y and z are consecutive integers and x<y<z,which of the following must be true? When a certain number is divided by 7,the remainder iS 0.If the remainder is not 0when the number is divided ...
Unlike spermatogenesis, which continues throughout adulthood, the main stages of oogenesis occur at the embryonic stage of development in mammals. Oogenesis and the production of primary oocytes occur throughout prenatal development, and by birth, primordial follicles have formed, in which the oocyte i...
affected distinct cell populations in these models, as it suggests that these subroutines of cell death are under strict spatial control. Kelepouras et al. also showed that intestinal apoptosis, rather than necroptosis, arises in mice after systemic TNF administration. Others have performed similar s...
Prior to ICI initiation, individuals should be informed of the potential diabetes risk and receive education on the symptoms and signs of hyperglycaemia and DKA so that they can seek medical attention as soon as symptoms occur. Blood glucose and HbA1c should also be checked routinely prior to IC...
The work presented here has been able to link the enhanced anti-tumour effects seen when selumetinib is combined with TMZ or docetaxel to enhanced DNA damage and apoptosis, respectively. Furthermore, our studies have also explored the rationale for sequence scheduling when MEK inhibitors and agents...
In which stage of interphase does DNA replication occur? When does DNA replication take place? A) During mitosis. B) Before a cell starts to divide. C) During cytokinesis. D) Continuously during the whole cell cycle. Which stage of mitosis proceeds to metaphase?
The BCL2 inhibitor venetoclax has fundamentally changed the approach to treating acute myeloid leukemia (AML) in patients who cannot tolerate intensive chemotherapy. The drug effectively underscores how our improved knowledge of molecular cell death pathways, especially concerning intrinsic apoptosis, can fi...
Aggresomes refer to an assemblage of aggregated or misfolded proteins that occur when the cell’s degradation system is overwhelmed. Takashaki et al. found that USP10 inhibits ubiquitinated protein-induced apoptosis by inducing aggresome formation; USP10 interacted with p62 and this interaction ...
patients19develop recurrence over a 5-year period, and relapse is almost inevitable in glioblastoma patients20. Why does this occur? Since most chemotherapeutic agents and radiotherapy treatments are designed to eliminate rapidly proliferating cancer cells, tumour relapse may be driven by non- or slow...