How is the cancer cell cycle different from a normal cell cycle? How is the cancer cell cycle different from a normal cell cycle? Provide a rationale for the answer. How is cancer a disease of the cell cycle? E
What does rhodopsin have to do with cell signaling? What are the initiator caspases in apoptosis signaling pathways? Where does detoxification occur in the cell? When does cell differentiation occur? Where does deamination occur in the cell?
Differential regulation of apoptotic cell death in senescent human cells. Exp. Gerontol. 39, 1713–1721 (2004). CAS PubMed Google Scholar Chen, Q. M., Liu, J. & Merrett, J. B. Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 ...
The breakthroughs in understanding HIV pathogenesis fueled subsequent research beyond the boundaries of unchecked viral replication. Uninterrupted CD4 T cell activation and apoptosis are the hallmarks of both HIV disease progression as well as the basis of a persistent inflammatory state, which is associat...
On one hand, caspases have the ability to cleave cell cycle regulators. For example, p21Cip1/Waf1, a cyclin-dependent kinase (CDK) inhibitor, is specifically cleaved by caspases upon induction of apoptosis [19]. This would suggest a potential mechanism for inducing proliferation in cells that ...
Deubiquitination is now understood to be as important as its partner ubiquitination for the maintenance of protein half-life, activity, and localization under both normal and pathological conditions. The enzymes that remove ubiquitin from target proteins
(Ozturk, 2015; Achi et al., 2000). Telomere extension is thought to occur during spermatogenesis not only with the help of telomerase, but also with the involvement of a recombination mechanism known as ALT. This is supported by the detection of telomeric RNA TERRA in spermatocytes (Reig-Vi...
The pathophysiology of OE formation is complex and multifactorial, much like endometriosis itself [21]. OEs tend to occur more often on the left ovary (60%), a trend attributed to factors such as the menstrual reflux theory and anatomical distinctions between the left and right hemipelvis [22...
Germ cell development has been difficult to study in vivo, because important early events occur after im- plantation. This difficulty is most evident in humans, when ethical issues are considered. In addition, limita- tions in the number of germ cells, their deep location within the embryo ...
What can occur if a plant loses control of the cell cycle? What would happen if cell division becomes uncontrolled? What would happen to the cell cycle in a cell in which cyclin was NOT broken down through mitosis? What happens if we have too little cell division? Does the cell cycle ha...