Differential regulation of apoptotic cell death in senescent human cells. Exp. Gerontol. 39, 1713–1721 (2004). CAS PubMed Google Scholar Chen, Q. M., Liu, J. & Merrett, J. B. Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 ...
11. Tumor proliferation: the Ki-67 protein 12. Gene apoptosis: tumor protein p53 and B-cell lymphoma 2 13. New methods for predicting chemotherapy response 14. Chemotherapy assay 15. Multigene biomarkers 16. PET assay 17. Use of chemotherapy predictors ...
with cell surface glycans and delivering signals that lead to disruption of cellular homeostasis.12–14 We discuss here the contribution of glycan–lectin interac- tions to the initiation, execution and resolution of apoptosis and their emerging roles in other cell death programs including autophagy. ...
The pathophysiology of OE formation is complex and multifactorial, much like endometriosis itself [21]. OEs tend to occur more often on the left ovary (60%), a trend attributed to factors such as the menstrual reflux theory and anatomical distinctions between the left and right hemipelvis [22...
Since this determination has been performed on the Roche Cobas analytical platform, inTable 1we provide the conversion of this URL into concentrations estimated by other commercially available assays to generalize the use of the URL to other assays used in the clinical practice. This is relevant, ...
Human amniotic epithelial cells (hAECs) maintain the plasticity of pregastrulation embryonic cells, having the potential to differentiate into all three germ layers. The potential of these cells to differentiate into cells expressing germ cell specific m
Finally, lipoprotein ingestion via macropinocytosis may also occur. Figure 2 Lipid-acquisition routes in cancer cells. Cancer cells can produce non-essential fatty acids from the primary nutrients glucose and glutamine. However, low nutrient availability and hypoxia compromises the ability to synthesise ...
cells within a mixed tumor population suggest that a dynamic reprogramming process may occur during the transition state [9,10,11,12]. This bidirectional conversion or so-called cancer cell plasticity may emerge as a challenge for cancer treatment [13,14]. Therefore, delineating the mechanisms of...
03 December 2015 investigation of living cells during cytokinesis Jen-Fang Hsu, Pei-Ying Hsieh, Hsin-Yun Hsu & Shinsuke Shigeto† In vivo, molecular-level investigation of cytokinesis, the climax of the cell cycle, not only deepens our understanding of how life continues, but it will...
Deubiquitination is now understood to be as important as its partner ubiquitination for the maintenance of protein half-life, activity, and localization under both normal and pathological conditions. The enzymes that remove ubiquitin from target proteins