CMLChronic phaseChronic myeloid leukaemia (CML) is a paradigmatic disease, as knowledge on the molecular pathology of CML has driven the development of targeted drugs, which finally led to a substantial improvement of the patients' prognosis. However, despite very potent drugs, such as Imatinib, ...
Why is multiple myeloma not a leukemia? What is pre-B cell acute lymphoblastic leukemia? Is leukemia a hereditary disease? How does leukemia start? What is the prognosis for acute leukemia? What is the Leukemia and Lymphoma Society? Is leukemia a chronic illness? Why is leukemia the most com...
Leukemia is categorized as acute or chronic based on the rate of proliferation of the leukemic cells. There are four major types of leukemia, two each for the predominant cell lineages—chronic/acute myeloid leukemia (CML and AML) and chronic/acute lymphocytic leukemia (CLL, ALL).3Cases of ca...
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M. et al. Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential. Leukemia 21, 1423–1430 (2007). Article CAS PubMed Google Scholar Ginestier, C. et al. ALDH1 is a marker of normal ...
prognosisprognostic scoressurvivalIntroduction: The outcome of chronic myeloid leukemia (CML) patients in chronic phase has changed after the introduction of tyrosine kinase inhibitors (TKIs). The life expectancy is actually similar to that of the general population. Prognostic stratification at baseline ...
Studies have also indicated that in gastric cancer patients with the p53 mutation, decreased expression of FBXW7 with distinctively poor prognosis was observed [25]. Further, it has been shown that FBXW7 and p53 cooperatively inhibited advanced and chromosomally unstable intestinal cancer. Moreover,...
LT-CML LT-FA LT-GaAs LT-LDPC LT-MRD LT-SSS LT1 LT1ESWTR LT2 LT2-FTS LT2ESWTR LT3 LTA LTAA LTAAC LTAB LTABC LTAC LTACFIRE LTACH LTACS LTAD LTAE LTAF LTAFC LTAFR LTAG LTAH LTAHAW LTAHB LTAI LTAIG LTALV LTAM LTAN ...
Suppression of HBV replication by Interferon alpha is almost always associated with remission in biochemical activity. Thus, an effective antiviral therapy is expected to improve its prognosis. 9 Unfortunately, although IFN-alpha has been reported to induce initial remission in almost 65% of the ...