The prognosis of CML has improved dramatically with the advent of tyrosine kinase inhibitors (TKIs) such as imatinib, dasatinib, and nilotinib, which have transformed CML from a fatal disease to a chronic, manageable condition. However, the optimal management of CML in adolescents and young adults...
Thus, the treatment of CML-BP remains one of the major challenges in the management of patients with CML. Although the overall prognosis in CML-BP seems to be better in children than adults, consistent data regarding the optimal management of CML-BP in children and adolescents are lacking give...
Adapt lipid targets to general health status and prognosis. Consider drug–drug interactions if therapy is needed. Assess together with thyroid assessment; hypothyroidism should be treated before start of TKI. Total cholesterol, high-density lipoprotein, low-density lipoprotein, triglycerides before start...
Younger patients with chronic myeloid leukemia do well in spite of poor prognosis indicators: results from randomized CML study IV. Ann Hematol 2014; 93:71-80.Kalmanti L, Saussele S, Lauseker M, Proetel U, Muller MC, Hanfstein B et al. Younger patients with chronic myeloid leukemia do ...
Prognosis of long-term survival considering disease-specific death in patients with chronic myeloid leukemia Leukemia, 30 (1) (2016), pp. 48-56 CrossrefView in ScopusGoogle Scholar 54 F Castagnetti, G Gugliotta, M Breccia, et al. The use of the EUTOS long-term survival score is strongly ...