In this issue of the European Journal of Haematology, Thielen and colleagues report on a population based study from the Netherlands of 3585 CML patients over a period of 23 years. The data show that prognosis of CML has profoundly improved after introduction of tyrosine kinase inhibitors (TKI)...
This paper describes how LSC functional assays, when combined with global transcriptome profiling, can be used to identify stem cell mRNA signatures that are linked to prognosis. CAS PubMed Google Scholar Goardon, N. et al. Coexistence of LMPP-like and GMP-like leukemia stem cells in acute ...
Adapt lipid targets to general health status and prognosis. Consider drug–drug interactions if therapy is needed. Assess together with thyroid assessment; hypothyroidism should be treated before start of TKI. Total cholesterol, high-density lipoprotein, low-density lipoprotein, triglycerides before start...
Prognosis of long-term survival considering disease-specific death in patients with chronic myeloid leukemia Leukemia, 30 (1) (2016), pp. 48-56 CrossrefView in ScopusGoogle Scholar 54 F Castagnetti, G Gugliotta, M Breccia, et al. The use of the EUTOS long-term survival score is strongly ...
A Nationwide Observational Study of Ponatinib in CML Patients Outside of Clinical Trials- The Israeli ExperienceBackground: The prognosis of elderly patients with acute myeloid leukemia (AML) is poor, and the best treatment is controversial. Since the majority of AML patients are older than 60 ...