Due to the complexity of NGS data and associated algorithms, NGS analysis is typically performed by bioinformatics specialists. To empower users who don’t have specialized bioinformatics training, platforms like Ion Torrent have created user-friendly, intuitive s...
The science of Bioinformatics, which is the melding of molecular biology with computer science, is essential to the use of genomic information in understanding human diseases and in the identification of new molecular targets for drug discovery. In recognition of this, many universities, government ...
The Center for Bioinformatics and Computational BiologyTieliu ShiThe Center for Bioinformatics and Computational Biology中国科学:生命科学(英文版)Jia,J. and Shi,T. (2017) Towards efficiency in rare disease research: what is distinctive and important? Sci. China. Life Sci., 60, 686-691.Towards ...
Learn about SAM & BAM files and how to read your raw alignment format in this blog, perfect for bioinformatics beginners.
The scope of Next-Generation Sequencing (NGS) and RNA sequencing (RNA-seq) are rapidly evolving and expanding. What is RNA Sequencing (RNA-Seq)? The growing field of RNA sequencing (RNA-Seq) seeks to elucidate the many roles of RNA in the modulation of cellular and biological processes, no...
What is the difference between 16S and metagenomic sequencing? Discover all you need to know in our expert guide.
The evolution of plants to efficiently transport water and assimilates over long distances is a major evolutionary success that facilitated their growth and colonization of land. Vascular tissues, namely xylem and phloem, are characterized by high specia
Iain Moal, PhD, Scientific Leader, Computational Antibody Engineering, GSK, on: ‘Learning antibody binding affinity using FACS and NGS’. Emerging targets and therapeutic approaches The second track of PEGS Europe 2023 is ‘Emerging targets and therapeutic approaches’, which will feature a range of...
TNseq – Drop-in replacement of Broad Institute MuTect/MuTect2. This pipeline is 10x faster with no down sampling. TNscope – Improved accuracy beyond Broad Institute Mutect/Mutect2, additional UMI functionality Tool options Sentieon pipelines usage ...
Finally, somatic copy number variations (CNVs) are assessed using specific bioinformatics procedures on mapped reads in matched melanoma samples. Although the NGS methodology may be also used for gene expression studies using RNA substrate, the main application is aimed at identifying mutations and ...