myelin basic protein have been explored to gain some insight into the protein's function. Available data suggest that in vivo the protein might have a highly ordered, compact structure that is defined by specific intramolecular interactions made possible by the protein's immediate lipid environment....
In PD as well as in MSA there is intracellular accumulation of an abnormally folded insoluble protein, alpha-synu- clein, in the form of Lewy bodies in PD and largely as oli- godendroglial, glial cytoplasmic inclusions (GCIs) in MSA. For this reason MSA and PD are classified as alpha-...
Protein S-100B, neuron-specific enolase (NSE), myelin basic protein (MBP) and glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and blood... In this study, data about protein S-100B, neuron-specific enolase, myelin basic protein and glial fibrillary acidic protein in cereb...
different GMB-derived metabolite, methylamine trimethylamine N-oxide (TMAO), was able to enhance BBB integrity by altering expression of annexin A1, a tight junction protein. TMAO was also able to limit LPS-mediated memory impairment by limiting microglial and astrocyte-mediated neuroinflammation [53]...
CSF proteomics (recognition of complex protein pat- terns) is a promising approach that has proven effective in oncology applications. Although no single marker currently satisfies the re- quirements for a useful biomarker for AD, research on multiple can- didate biomarkers may provide a panel or...
Histopathological detection of intracortical MS lesions improved with the use of myelin protein immunohistochemistry in the beginning of the 21stcentury. Using immunohistochemistry for myelin basic protein (MBP) and proteolipid protein (PLP), Bö and colleagues shed more definitive light on the extent ...
(myelin basic protein) S100B (Calcium-Binding Protein B) and its isoforms s100A1B and s100BB GFAP (glialfibrillary acidic protein) GFAP breakdown products (GFAP-BDP) Angiopoietins-1/2(Ang-1/2) Marker Origins Neuron Neuron Axons and presynaptic terminals Axons and presynaptic terminals Neuronal ...
Myelin tetraspan family proteins but no non-tetraspan family proteins are present in the ascidian (Ciona intestinalis) genome The original PSI-BLAST results were used for the sequences where no rules could be induced. We compared the area under the ROC (AUROC) for homology induction and PSI-BLA...