Pediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology to epidemiology. Use of model organisms and in vitro techniques relevant to developmental biology and medicine are ...
生物育种|鸡胚操作技术 30 Experiments on the Chick Embryo Tools and Techniques 99 -- 11:17 App 生物育种|鸡胚操作技术 Primary Culture of Chicken Embryos Step 1 Preparation 15 -- 20:29 App Introduction to Protein Synthesis 54 -- 27:55 App translation Elongation Termination Stages of Protein Syn...
摘要: Test for the presence of protein 14-3-3 in the CSF of patients with suspected sCJD has been used for many years but has been in debate recently. Lumbar puncture is routinely done for CSF analysis of 14-3-3 by neurologists in suspected case of CJD...收藏...
Myelin basic protein (MBP) was serially measured in 177 CSF samples of 33 patients with leptomeningeal metastases and in 34 cancer controls. The mean level in cancer controls (free of neural involvement) was 5.7 ± 0.33 ng/ml (normal < 5 ng/ml) with abnormal elevation of MBP detected in ...
Protein phosphorylation is recognized as the primary mechanism for the transduction of extracellular stimuli into intracellular events (Cohen, 1982; Nestler et al.,1984). Ineukaryotes, for example, all of the biochemical actions of cAMP have been attributed to activation of cAMP-dependent protein kina...
Here, we quantified NfL in CSF and blood in R6/2 mice using the ultra-sensitive immunoassay, Single molecule array (Simoa)-based immunoassay technology15,16,17. We found that NfL was elevated in R6/2 mice in both fluids; its level was significantly associated with measures of clinical and ...
Glial fibrillary acidic protein (GFAP) is expressed by astrocytes in the central nervous system (CNS), but also by immature and regenerative Schwann cells
In recent years, based on the rise of antibody-based therapies, new biotherapeutic approvals have favored mammalian hosts. However, not only has extensive research elevated our understanding of microbes to new levels, but emerging therapeutic molecules also facilitate their use; thus, is it time ...
CSF-1 receptor signaling in myeloid cells. Cold Spring Harb. Perspect. Biol. 6, a021857 (2014). Article PubMed PubMed Central Google Scholar Niogret, C., Birchmeier, W. & Guarda, G. SHP-2 in lymphocytes’ cytokine and inhibitory receptor signaling. Front. Immunol. 10, 2468 (2019). ...
Mollenhauer, B. et al. Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration.Exp. Neurol.213, 315–325 (2008). CASPubMedGoogle Scholar Buch, K. et al. Tau protein. A potential biological indicator for early detection of Alzheimer...