摘要: The recent observation of GTP-promoted polymerization of a single septin polypeptide suggests that this protein has tubulin-like biochemical properties. This model cannot, however, explain the GTP-biochemistry of heteromeric septin complexes from cytosol....
(biochemistry) an organic molecule in which a nitrogenous heterocyclic base (or nucleobase), which can be either a double-ringed purine or a single-ringed pyrimidine, is covalently attached to a five-carbon pentose sugar (deoxyribose in DNA or ribose in RNA). When the phosphate group is covale...
We have 6 known classes of enzymes in biochemistry and each class is unique because of the type of chemical reaction it is involved in and catalyzes. The 6 classes of enzymes are oxidoreductase, transferase, hydrolase, lyase, isomerase, and ligase (class 1 to 6 in the given order). To...
Some molecules that are similar to nucleotides, some of them serving as intermediates in the process of nucleotide synthesis, are important in biochemistry as well. A nucleoside, for example, is a nitrogenous base linked to a ribose sugar; in other words, it is a nucleotide missing its phospha...
In general, their specific roles in the viral replication cycle remain poorly understood at present. The SF1 helicase protein of viruses classified in the order Nidovirales is encoded in replicase open reading frame 1b (ORF1b), which is translated to give rise to a large polyprotein ...
Some molecules that are similar to nucleotides, some of them serving as intermediates in the process of nucleotide synthesis, are important in biochemistry as well. A nucleoside, for example, is a nitrogenous base linked to a ribose sugar; in other words, it is a nucleotide missing its phospha...
In this review, we present the basis for an emerging consensus on how dynamin functions. Three properties of dynamin are strongly supported by experimental data: first, dynamin oligomerizes into a helical polymer; second, dynamin oligomer constricts in the presence of GTP; and third, dynamin ...
Non-alcoholic fatty liver disease (NAFLD) is a serious health problem due to its high incidence and consequences. In view of the existing controversies, new therapeutic options for NAFLD are still being sought. Therefore, the aim of our review was to evaluate the recently published studies on ...
The purpose of this review is to identify the interpretive limits of cellular biochemistry using, largely, the tools of physical chemistry. We illustrate this approach using two major concepts in cancer: carcinogenicity and cancer recurrences. Cells optimize the chemical performance of enzymes and ...
Biochemistry TP 7.2 g/dL Alb 4.2 g/dL Ferritin 98 ng/ml T-Bil 0.9 mg/dL D-Bil 0.1 U/L ID-Bil 0.8 U/L AST 37 U/L ALT 26 U/L LDH 227 U/L ALP 134 U/L [gamma]-GTP 13 U/L BUN 10.9 mg/dL Cr 0.63 mg/dL eGFR 69.1 ml/min/1.73 [m.sup.2] T-chol 199 mg/dL IL-...