What is exon shuffling and what is the role of mobile DNA elements in this process? If an antibiotic binds to a 5OS subunit, what cellular process will be inhibited? A. DNA replication B. Intron excision C. Translation D. Transcription ...
Exon: Exons are protein-coding regions in a DNA (deoxyribonucleic acid) sequence. Splicing removes introns from exons that are present in a messenger ribonucleic (mRNA) post-transcription process. Answer and Explanation:1 STRs or short tandem repeats are short repetitive DNA sequences that are usu...
What is a plasmid? How is a plasmid used in gene splicing? Why are frameshift mutations one of the most severe types of mutations? (a) More than one gene is affected (b) They cannot be reversed (c) More than one amino acid or the entire protein is affected (d) They occur only in...
Silent mutationscreate problems with exonic splicing enhancers (ESEs), resulting in changes in mRNA processing of the genetic information. ESE motifs are sequences between three and eight nucleotides long and are found near the end of exons within what will be the coding sequence of the final mR...
Kornblihtt has pre- viously shown that transcription and splicing are coupled; differential splicing of exons is affected by the elongation rate, which in turn depends on the transcriptional promoter. Some viral transcriptional activators, such as VP16, increase exon skipping, whereas others, such ...
splicing requires the presence of several cis-acting sequences in the HIV genome and therefore the presence of MS RNA reduces the possibility of measuring proviruses with large deletions [78]. The relative decrease in MS RNA level upon ART initiation is more prominent than that of US RNA [79...
More than 100 different transcripts can be derived from the HIV unspliced (US) genomic RNA by alternative splicing, although it is unclear if all of them are present in infected individuals [57, 58]. These include incompletely, or singly spliced and completely, or multiply spliced (MS) transc...
Furthermore, lncRNAs can change the alternative splicing of an exon or affect promoter activity. For example, the long noncoding RNA highly upregulated in liver cancer (HULC) can specifically bind to the Y-box binding protein 1 (YB-1) promoter, thus silencing the mRNA of this gene. ...
the use ofmultiple 3' cleavage sitesin a single exon. (Every intron has a 5' and3' splice site.) As illustrated in Figure 3, the end result is the same as with alternative splicing: different mRNA molecules are produced from a single protein-coding gene. Clearly, contrary to the convent...
An exon isthe portion of a gene that codes for amino acids. In the cells of plants and animals, most gene sequences are broken up by one or more DNA sequences called introns. Is Poly a sequence encoded in DNA? Most of the RNA found in our cells is built using our DNA genome as ...