Both exon shuffling and alternative splicing of LRR repeats may be important mechanisms for generating diverse ligand-binding specificities as immune receptors. Besides their potential immune role, expression a
Alternative splicing (AS) is a central mechanism for physiological regulation of protein diversity1,2,3. AS of pre-messenger RNA (mRNA) occurs through modulation oftrans-acting splice accessory factors, RNA-binding proteins (RBPs), and theircis-acting binding sites (splice signals such as the 3...