Analysis of CD117-negative gastrointestinal stromal tumors. World J Gastroenterol 2005;11:1052–1055. Article CAS PubMed PubMed Central Google Scholar Wardelmann E, Losen I, Hans V et al. Deletion of Trp-557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated...
Adjuvant therapy with imatinib is commonly used to reduce the likelihood of disease recurrence after primary surgery, and for this reason assessing the prognosis of newly resected tumors is one of the most important roles for pathologists. Approximately 15% of GISTs are negative for mutations in ...
Surgery is the cornerstone of treatment for extremity STS; the goal is complete excision with negative microscopic margins (R0 resection).[5]Frequently, these tumors develop a "pseudocapsule," which arises as a result of the reactive, compressed surrounding tissue. It is desirable to resect a ma...
aA study of CD117 expression in dermatofibrosarcoma protuberans and cellular dermatofibroma CD117表示的研究在dermatofibrosarcoma protuberans和多孔的dermatofibroma [translate] aIf you do not leave me , I will in life and death 如果您不留下我,我意志在生与死 [translate] aAccess to the registry key...
(-), CD10 (+), CD22 (+), CD20 variably (+), CD19 (+), HLA-DR variably (+), CD34 partial (+), CD56 partial (+), Tdt (+), and negative for the remaining lymphoid and myeloid markers tested, including CD14, CD5, CD7, CD33, CD13, CD3, CD4, CD8, CD117, CD16, and MPO...
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Analysis of CD117-negative gastrointestinal stromal tumors. World J Gastroenterol 2005;11:1052–1055. 21 Wardelmann E, Losen I, Hans V, et al. Deletion of Trp- 557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated with metastatic behavior of gastrointestinal ...
Adjuvant therapy with imatinib is commonly used to reduce the likelihood of disease recurrence after primary surgery, and for this reason assessing the prognosis of newly resected tumors is one of the most important roles for pathologists. Approximately 15% of GISTs are negative for mutations in ...
tryptase/CD117+ mast cells, and endocrine cells.5 This cellular infiltrate is commonly paralleled by the subtle increase of para-inflammatory molecules or their genes (interleukin 1尾 (IL1尾), tumour necrosis factor 伪 (TNF伪), IL6, IL6r, transforming growth factor 尾 (TGF尾), IL10, trypt...
CD138,cLambda,CD28,CD200,and CD117.Fluorescence in situ hybridization gene testing of the bone marrow suggested 1q21 gene amplification,but cytogenetic testing showed no clonal abnormalities.Colonic mucosa and bone marrow biopsy tissues were negative for Highman Congo red staining.The patient was ...