Diffuse brainstem glioma is a rare disease in adults. Radiotherapy (RT) is usually considered to be the standard treatment. However, the role of chemotherapy in treating relapses after RT is unclear, and this study aimed to assess the use of temozolomide (TMZ) in this situation. We conducted...
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We now suggest vorasidenib rather than watchful waiting or postoperative radiation therapy (RT) plus chemotherapy in most patients with residual disease and no uncontrolled symptoms after maximal safe resection of a newly diagnosed grade 2 IDH-mutant diffuse glioma. However, clinicians must use ...
Secondly, there are molecular reasons why the COVID-19 virus may impact on cardiovascular health in patients. So, it's been shown that the angiotensin II receptor found both in the heart but also in lung tissue and alveolar cells, is a receptor for the COVID-19 virus. And there have be...
period that the hematoma is not yet organized; in this case, the goal is the complete removal, preventing recurrence of bleeding and functional worsening.1,14,15However, before indicating the surgical procedure, the main differential diagnosis (pontine glioma and multiple sclerosis) must be excluded...
The second group of disorders causing generalised VF defects are retinal causes, where diffuse photoreceptor pathology affects the visual-field profoundly. Leber congenital amaurosis (LCA) is a group of monogenic inherited retinal degenerations that typically show early-onset and severe visual dysfunction...
What is the WHO glioma classification? What is the WHO classification of dental trauma? What is basement membrane's definition? What does it consist of? What is the structure of a tornado? What is a corticated ossicle? What is the MIT classification of soil? What is the WHO classification...
In gliomas, an important receptor is natural killer receptor protein 1 (CD161), which is encoded by the KLRB1 gene (“Killer Cell Lectin Like Receptor B1 gene”) and acts as a suppressor of T cell cytotoxicity and NK cell activity. In a cohort of 313 glioma patients, Di and colleagues ...
A major challenge in identifying the genetic determinants of stroke is fully understanding the complexity of the phenotype. Aims: Our narrative review is needed to improve our understanding of the biological pathways underlying the disease and, through this understanding, to accelerate the identification...
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