Molecular epidemiologic studies of diffuse WHO grade II glioma (diffuse low-grade glioma, DLGG) have contributed greatly to our knowledge of these slow-growing but highly infiltrative tumors. Such studies have yielded valuable insights into factors that modify risk of disease development including ...
The current World Health Organization classification recognizes three histological types of grade II low-grade diffuse glioma (diffuse astrocytoma, oligoastrocytoma, and oligodendroglioma). However, the diagnostic criteria, in particular for oligoastrocytoma, are highly subjective. The aim of our study was...
diffuse glioma (WHO grade II) Diffuse gliomas are low-grade tumours and comprise the histological subtypes of astrocytoma, oligoastrocytoma and oligodendroglioma. Although they have a protracted natural history of years or occasionally decades, and may not need immediate therapy, these tumours invariably...
Magnetic resonance imaging (MRI) depicting pediatric low-grade glioma arising in thea. Cerebellum,b. Thalamus, andc. Occipital Lobe. Hematoxylin and eosin (H&E) staining highlighting the hallmark histologic features ofd. Pilocytic astrocytoma,e. Diffuse astrocytoma,f. Pleomorphic xanthoastrocytoma,g. ...
Gorovets D, Kannan K, Shen R, Kastenhuber ER, Islamdoust N, Campos C, Pentsova E, Heguy A, Jhanwar SC, Mellinghoff IK, Chan TA, Huse JT (2012) IDH mutation and neuroglial developmental features define clinically distinct subclasses of lower grade diffuse astrocytic glioma. Clinical cancer...
Patients and methods A retrospective analysis was carried out on the epidemiology, clinical characteristics, tumour location, histology, treatment, outcome and long-term sequelae of 111 patients diagnosed with low-grade glioma in the Niño Jesús Children's Hospital of Madrid from January 2002 to ...
Low-grade diffuse gliomas WHO grade II (diffuse astrocytoma, oligoastrocytoma, oligodendroglioma) are characterized by frequent IDH1 / 2 mutations (>80%) ... H Ohgaki,P Kleihues - 《Brain Tumor Pathology》 被引量: 221发表: 2011年 Intratumoral homogeneity of MGMT promoter hypermethylation as demon...
METHODS. English-speaking patients ages 0-21 with diffuse intrinsic pontine glioma, glioblastoma multiforme, or secondary HGG were eligible. Key decision making visits (e.g. MRI reviews) and patient/parent semi-structured interviews were serially audio-recorded. Oncologist questionnaires were obtained. ...
Surgical paradigms in diffuse low-grade glioma: insular glioma case illustrationAstrocytomaGangliogliomaLow-grade gliomaMulticentric gliomaPlatelet-derived growth factor receptor amplificationTumor progressionSupratentorial low-grade gliomas comprise a group of primary central nervous system neoplasms with ...
Despite the small number of cases, our findings suggest the surgical benefit of awake surgery for the supratotal resection of diffuse frontal LGGs. 展开 关键词: awake brain mapping frontal lower-grade gliomas neurocognitive functions working memory ...