What causes early-onset Alzheimer’s? While the exact causes of early Alzheimer’s disease aren’t fully understood yet, scientists believe it’s caused by the abnormal build-up of two proteins in the brain known as amyloid and tau. At a basic level, the failure of these proteins to funct...
even the combined association of amyloid and tau pathology does not inevitably need to dementia over age 65.Other pathological factors may play a leading or an accelerating role in age-associated cognitive decline,including vascular small vessel disease,neuroinflammation and Lewy Body pathology.Conclusion...
amyloid and tau are the two dysfunctional proteins, and they can be measured in a patient's spinal fluid. The form of abnormal tau that can be involved in FTD is different than in Alzheimer's disease, which adds to the complexity of diagnosis when using...
amyloid and tau are the two dysfunctional proteins, and they can be measured in a patient's spinal fluid. The form of abnormal tau that can be involved in FTD is different than in Alzheimer's disease, which adds to the complexity of diagnosis when using...
The study of protein aggregation, and amyloidosis in particular, has gained considerable interest in recent times. Several neurodegenerative diseases, such as Alzheimer’s (AD) and Parkinson’s (PD) show a characteristic buildup of proteinaceous aggregates in several organs, especially the brain. Des...