it puts that immune cell to sleep. The sialic acids are telling the immune cell, "Hey, this cell's all right. Nothing to see here, move along. Look somewhere else." So in other words, as long as our cells
And so this is what we're doing in my lab. We're developing new medicines that are basically cell-surfacelawnmowers-- molecules that go down to the surface of these cancer cells and just cut off those sialic acids, so that the immune system can reach its full potential in eliminating t...
they are a low level toxin. The purpose of lectins is to discourage other animals from eating that life form. By triggering a negative reaction in the predator, that life form is then viewed as an undesirable food source. Hence, aiding its future survival. ...
The expression and distribution of specific glycans on the surface of a cell are important for various cellular functions. Imaging these glycans is essential to aid elucidation of their biological roles. Here, utilizing methods of direct fluorescent glycan imaging, in which fluorescent sialic acids ...
aCalculate the number of moles of sialic acids per mole of 计算摩尔的数量硅铝层酸每摩尔 [translate] a他已经邀请我同她呆在一起。 He already invited mine to stay with her in the same place. [translate] a我不想当坏女孩 I do not want to work as bad girl [translate] awhats a fuck?
Sialic acids are often the platform for orthogonal chemical functionalization on cell surfaces. This is accomplished via techniques such as metabolic glycoengineering, yet the ability of sialidases to remodel unnatural sialic acids incorporated within the glycome is unknown. Their substrate specificities ...
The essays within this book—all of which appear here for the first time—are philosophical explorations of the nature of persons. Those comfortable using the word ''analytic'' to describe the kind of philosophy that now thrives in the philosophy departments of most Anglophone universities will sa...
Multiple co-regulatory elements and IHF are necessary for the control of fimB expression in response to sialic acid and N-acetylglucosamine in Escherichia coli K-12. Mol. Microbiol. 2007, 63, 1223–1236. [Google Scholar] [CrossRef] Liu, Y.; Han, R.; Wang, J.; Yang, P.; Wang, F....
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Moreover, all seven cysteines involved in disulfide linkages of template SV5 are conserved in the MuV target model (Figure 2). The stalk region (residues 1-144) of MuV HN was not modeled because the equivalent amino acids were not visible in the electron density maps of crystallized SV5 ...