Sialic acids are predominantly found at the terminal ends of glycoproteins and glycolipids and play key roles in cellular communication and function. The process of sialylation, a form of post-translational modification, involves the covalent attachment of sialic acid to the terminal residues of oligosa...
Current studies are exploring agents that target sialic acid residues on sialoglycans or the sialylation process. These efforts are particularly focused on the fields of cancer therapy, stroke treatment, antiviral strategies, and therapies for central nervous system disorders. In this review, we aimed...
Therefore, we developed an air-liquid interface culture system for differentiated porcine respiratory epithelial cells to study the effect of virus-induced cellular damage. In our well-differentiated cells, α2,6-linked sialic acid is predominantly expressed on the apical surface and the basal cells ...
Furthermore, sialic acid plays an important role in the interaction between osteoclasts and other cells. It is widely involved in biofilm recognition, fusion, and receptor‒ligand interactions. As a tumor cell line capable of bone metastasis, the PC3 prostate cancer cell line37can generate tumor-...
Physiological function, application and manufacturing method of sialic acid[J]. Science and Technology of Food Industry, 2014, (03): 363-368. DOI: 10.13386/j.issn1002-0306.2014.03.035 [10] Research progress in the physiological functions and applications in food of inulin[J]. Science and ...
The relationship between dietary vitamin A intake and the levels of sialic acid in the breast milk of lactating women[J]. Journal of Nutritional Science and Vitaminology,2013,59(4):347−351. doi: 10.3177/jnsv.59.347 [15] 尹晓娟. 化学酶法合成LNT系列人乳寡糖[D]. 济南:山东大学, 2013. [...
[188]. FF total sialic acid (FF-TSA) levels positively correlated with germinal vesicle oocytes and metaphase I oocytes. possibly as a part of the natural maturation process or as a response to counteract the effects of ROS during oocyte development. On the other hand, there was no ...
chromatography on phosphorylethanolamine-agarose, which isolates the pentraxins and separates limulin from the other sialic acid-binding lectins of the plasma, followed by fetuin-Sepharose, which binds limulin and separates it from Limulus C-reactive protein, the most abundant pentraxin of the plasma...
The role of the carbohydrate component of sex steroid-binding globulin (SBP) from human blood in the glycoprotein interaction with the recognition system for SBP-estrogen complexes in human decidual endometrium plasma membrane was studied. It was shown that the removal of N-acetylneuraminic acid res...
Furthermore, sialic acid plays an important role in the interaction between osteoclasts and other cells. It is widely involved in biofilm recognition, fusion, and receptor‒ligand interactions. As a tumor cell line capable of bone metastasis, the PC3 prostate cancer cell line37can generate tumor...