GAMIAN A., JONES C., LIPIŃSKI T., KORZENIOWSKA-KOWAL A., RAVENSCROFT N.: Structure of sialic acid-containing O-specific poly- saccharide from Salmonella enterica serovar Toucra O48 lipopolysaccharide. Eur.J.Biochem. 267, 3160-3166 (2000)....
The reverse reaction can be exploited for the synthesis of sialic acid and some of its derivatives. The structure of the enzyme from Escherichia coli has been determined to 2.2 A resolution by X-ray crystallography. The enzyme is shown to be a tetramer, in which each subunit consists of an...
摘要: Focuses on a derived structure of the putative sialic acid transporter from Escherichia coli which predicts a novel sugar permease domain. Role of the genes nanA and nanT in the catabolism of sialic acid; Confirmation of organization by physical mapping techniques....
The sialic acid binding site is near the centre of the protein, lined by residues from four helices (Tm1-Tm3 and Tm6) (Fig.1b). The electron density in this site corresponds to Neu5Ac in its β-anomeric form (Fig.1c) as seen in theHaemophilus influenzaeperiplasmic binding protein (Sia...
Crystal structure of the polysialic acid-degrading endosialidase of bacteriophage K1F. Nat. Struct. Mol. Biol. 12, 90–96 (2005). Article CAS PubMed Google Scholar Chan, Y. M., Bonnemann, C. G., Lidov, H. G. & Kunkel, L. M. Molecular organization of sarcoglycan complex in ...
Many orthomyxoviruses and paramyxoviruses possess a neuraminidase that will remove sialic acid from glycoproteins. The primary receptor for these viruses is sialic acid. The neuraminidase may allow the virus to penetrate through mucus to reach a susceptible cell. It also removes sialic acid from ...
terminal trisaccharide epitope consisting of two molecules of sialic acid linked to galactose, a structure reflecting the terminal region of human ganglioside ... S Salloway,LA Mermel,M Seamans,... - 《Infection & Immunity》 被引量: 255发表: 1996年 Glucose oxidase from Aspergillus niger: the...
Structures of asparagine-linked oligosaccharides of the glycoprotein fetuin having sialic acid linked to N-acetylglucosamine In the accompanying paper (Bendiak et al., 1989), the separation of a series of oligosaccharides released from asparagine residues of fetuin was described... DA Cumming,CG Helle...
An unsubstitutedN-acetylgalactosamine unit and a Galβ1 → 3GalNAc disaccharide were prominent O-linked constituents, with the disaccharide serving as a core unit for the attachment of sialic acid residues to form tetra- and trisaccharides. A branched core structure, Galβ1 → 3(GlcNAcβ1 → ...
An unsubstituted N-acetylgalactosamine unit and a Gal beta1 --> 3GalNAc disaccharide were prominent O-linked constituents, with the disaccharide serving as a core unit for the attachment of sialic acid residues to form tetra- and trisaccharides. A branched core structure, Gal beta1 --> 3(...