Plasma cells are a type of white blood cell that produces antibodies. An important part of the immune system, plasma cells serve...
The possibility that anti-idiotypes might serve as physiological regulators of Ig production by B cells is supported by the consistency with which mice are able to form Abs to idiotypes of Igs from...Jerne, NK (1971) What precedes clonal selection? In: Ontogeny of acquired immunity. Elsevier,...
Clonal deletion through apoptosis. These fates are controlled by the duration and strength of the activation of specific BCRs on the cell surface. BCRs recognize and facilitate the processing of antigens—a process that, with few exceptions, is dependent on help from T cells. What Are B-Cell...
In game theory, a solution concept in which players in a game are aware of the strategies of the other players but do not deviate from their own, because they do not have anything to gain; it will be disadvantageous to deviate (to 'cheat'). ...
The short-lived plasma cells produce a secreted form of the B cell receptor to promote antigen clearance by the immune system before undergoing apoptosis (usually within 3-5 days). The long-lived plasma cells and memory B cells respectively reside in the bone marrow and circulation for many ...
role of NK cells and T cells in multiple sclerosis Chu Xie, Signal Transduction and Targeted Therapy, 2024 Automated Classification of Intramedullary Spinal Cord Tumors and Inflammatory Demyelinating Lesions Using Deep Learning Zhizheng Zhuo, Radiology: Artificial Intelligence, 2022 mTOR Inhibitor Therapy ...
cells per million cells with 10 copies HIV RNA per cell, or 1 HIV RNA+ cell with 100 copies per cell. To discriminate between these possibilities, and to determine whether frequencies of HIV RNA+ cells or copy numbers per cell (or both) are changed upon ex vivo virus stimulation, a ...
Epstein-Barr virus induced lymphoproliferative tumors in severe combined immunodeficient mice are oligoclonal HEREDITARY SPHEROCYTOSISSevere combined immunodeficient (SCID) mice reconstituted with lymphocytes from Epstein-Barr virus (EBV) negative human donors develop ... P Pisa,MJ Cannon,EK Pisa,... -...
Cell surface proteins are of special interest for the understanding of how CHO cells react to their environment while maintaining growth and survival phenotypes, since they enable cellular reactions to external stimuli and potentially initiate signaling pathways. To provide deeper insight into functions ...
The liver is essential for processes such as metabolism, drug detoxification and plasma protein production. The two major parenchymal cell types in the liver are hepatocytes and biliary epithelial cells (BECs; cholangiocytes). Hepatocytes perform most of the liver functions, while bile ducts formed...