Voltage-gated K+ channel activity in human prostate cancer cell lines of markedly different metastatic potential: distinguishing characteristics of PC-3 and LNCaP cells. Prostate 46, 262-274.Laniado ME, Fraser SP, Djamgoz MB. Voltage gated K(+) Channel activity in human prostate cancer cell ...
Pharmacological activation of rapid delayed rectifier potassium current suppresses bradycardia-induced triggered activity in the isolated guinea pig heart. Hansen et al. J.Pharmacol.Exp.Ther., 2007;321:996 A dual potassium channel activator improves repolarization reserve and normalizes ventricular action ...
Na+ Channel Activity in C×43-Defident Myocytes. Introduction: Dynamic interplay between active and passive electrical properties of cardiac myocytes is based on interrelationships between various channels responsible for depolarizing and repolarizing ionic currents and intercellular conductances. Mice with ...
the tetanic response. Normally, aerobic metabolism of ATP and creatine phosphate provides energy for contraction. With prolonged activity, when oxygen availability may be insufficient, less efficient anerobic metabolism takes over. This can cause an increase in lactate production, which is a factor in...
Voltage-gated Na + channel activity and connexin expression in Cx43-deficient cardiac myocytes. J Cardiovasc Electrophysiol. 1999; 10 :1390–1401.Johnson CM, Green KG, Kanter EM, Bou-Abboud E, Saffitz JE, Yamada KA (1999) Voltage-gated Na+ channel activity and connexin expression in Cx43-...
View and buy high purity Dofetilide. KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr). Cited in 5 publications.
Handbook of Experimental Pharmacology, 2017, 164. Purkerson-Parker, S.L.; et al. Brevetoxin derivatives that inhibit toxin activity. Chemistry & Biology, 2000, 7:385-393. * Only for research. Not suitable for any diagnostic or therapeutic use. Send Inquiry Voltage-gated Na+ Channel SUBMIT ...
Voltage-gated potassium channel Potassium channel KvAP, structure in a membrane-like environment. Calculated hydrocarbon boundaries of the lipid bilayer are
R. Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol. Brain 139, 2164–2181 (2016). Article PubMed PubMed Central Google Scholar Ghovanloo, M. R., Dib-Hajj, S. D., Goodchild, S. J., Ruben, P. C. & Waxman, S. G. Non-psychotropic...
to measure ion channel function by neurotoxin-activated ion flux, and to detect VGSC proteins (the first member of this family to be studied biochemically) by high affinity binding of the neurotoxins tetrodotoxin, saxitoxin, and scorpion toxin (discussed later in this chapter). However, the molecu...