KC channel currents set the resting membrane potential, control action potential duration, control the rate of action potential firing, control the spread of excitation and Ca2C influx, and provide active opposition to excitation. To support these varied functions, there are a large number of KC ...
www.analog.com Analog Devices | 35 14-Channel, High-Voltage Data- Acquisition Systems R EGULAT OR D ISABLED VOLTAGE APP LIED TO DCIN CHECK DI E T EMPER AT UR E YES DIE TEMP > +1 45°C? NO CHECK SHDNL SHDNL ACTIV E? YES NO REGULATOR ENAB LED CHECK VAA VAA < VPOR_RISING YES...
Endogenous CCAT is predicted to be a 75 kDa protein; therefore, nuclear translocation of CCAT is likely to involve an active process rather than passive diffusion across nuclear pores. To estimate the rate of CCAT import into the nucleus, we used fluorescence recovery after photobleaching (FRAP) ...
Restraint alters the expression of 10 voltage-gated ion channel transcripts in the pPVT of females, but only 3 in males. Introduction Habituation to repeated stress refers to a progressive decrease in the stress response following multiple exposures to the same, mild-to-moderately intense homotypic ...
To understand the molecular basis underlying this mode of action, we used nuclear magnetic resonance to delineate the atomic details of the interaction between the VSD of the voltage-gated potassium channel KvAP and the spider-venom peptide VSTx1. Our data reveal that the toxin interacts with ...
The combination of in vitro multi-electrode arrays (MEAs) and the neuronal differentiation of stem cells offers the capability to study human neuronal networks from patient or engineered human cell lines. Here, we use MEA-based assays to probe synaptic f
All living organisms use active and passive proton transport mechanisms to control intracellular pH and proton gradients across cell membranes. Passive mechanisms, mediated by ion channels, let protons flow along their electrochemical gradient in response to specific signals. In animal cells, two major ...
voltage-gated sodium channelssodium currentventricular myocytesmiceaction potentialsimmunofluorescenceconfocal microscopyNa+ Channel Activity in C×43-Defident Myocytes. Introduction: Dynamic interplay between active and passive electrical properties of cardiac myocytes is based on interrelationships between various ...
8.3.3.1 Buck-Boost Converter Outputs The Buck-Boost converter can be used to provide power to the current output stage or the voltage output stage by enabling the Buck-Boost converter and connecting the power supplies as shown in Figure 100. Additional passive filters can optionally be added ...
9.3.1.2.1 DAC Register Synchronous and Asynchronous Updates The update mode for each DAC channel is determined by the status of its corresponding SYNC-EN bit. In asynchronous mode, a write to the DAC data register results in an immediate update of the DAC active register and DAC output on ...