Bick R.L., Walenga J., Fareed J., Hoppenstaedt D.A.: Unfractionated heparin, low molecular weight heparins, and pentasaccharide: basic mechanism of action, pharmacology, and clinical use. Hematol. Oncol. Clin. North Am. 2005, 19, 1....
Unfractionated Heparin, Low Molecular Weight Heparins, and Pentasaccharide: Basic Mechanism of Actions, Pharmacology, and Clinical Use 来自 NCBI 喜欢 0 阅读量: 76 作者: RL Bick,EP Frenkel,J Walenga,J Fareed,DA Hoppensteadt 展开 摘要: During the past decade, a large number of new ...
We aimed to identify attributing factors to the interindividual variabilities of the infusion rates in unfractionated heparin therapy. We included patients who required unfractionated heparin therapy to achieve the target APTT after cardiac surgery betwe
Pharmacotherapeutic aspects of unfractionated and low molecular weight heparins. Drugs. 1990;40(4):498–530. https://doi.org/10.2165/00003495-199040040-00003. Article CAS PubMed Google Scholar Hirsh J, Raschke R, Warkentin TE, Dalen JE, Deykin D, Poller L. Heparin: mechanism of action, ...
Apart from its noble anticoagulant properties, heparin and its derivatives can interact and modulate proteins involved in different biological process such as inflammation [2] and angiogenesis [3]; yet, its mechanism of action are still under debate. Furthermore, heparin broader use is still ...
Heparin historyLaboratory monitoringMechanism of actionNatural polysaccharidesNew scheme of coagulationPentasaccharideTranslational medicineFollowing a chance discovery made by a medical student who was searching for a clot-promoting activity in tissue extracts, it took 15-20years to attain the therapeutic ...
Heparin historyPentasaccharideAnticoagulationDeep venous thrombosisMechanism of actionNew scheme of coagulationClinical trialsLaboratory monitoringTranslational medicineFollowing a chance discovery made by a medical student who was searching for a clot-promoting activity in tissue extracts, it took 15-20 years ...
Unfractionated heparin (UFH) and low-molecular weight heparin (LMWH) are well defined anticoagulant agents. Recent data suggest that both LMWH and UFH may also have potent anti-inflammatory properties; however, their mechanism of action responsible for the anti-inflammatory effect is not yet fully ...
SummaryUnfractionated heparin (UFH) and low-molecular weight heparin (LMWH) are well defined anticoagulant agents. Recent data suggest that both LMWH and UFH may also have potent anti-inflammatory properties; however, their mechanism of action responsible for the anti-inflammatory effect is not yet ...
Recent evidence suggests that the clinical outcomes of unfractionated heparin therapy in children are poor, as determined by target-range achievement and adverse-event rates. These reports of poor outcomes may be related to an age-dependent mechanism of action of unfractionated heparin. Furthermore, ...