Low-molecular-weight heparinPentasaccharideAntithrombinAnticoagulantHeparin cofactor IIThrombinFactor XaThrombosisThe anticoagulant properties of the glycosaminoglycan heparin have made it an invaluable drug for the prophylaxis and treatment of thrombosis. These properties result from the ability of the ...
Heparin Monopotassium phosphate may increase the hyperkalemic activities of Heparin. Hexafluronium The therapeutic efficacy of Monopotassium phosphate can be decreased when used in combination with Hexafluronium. Hexocyclium The therapeutic efficacy of Monopotassium phosphate can be decreased when used in ...
Fondaparinux Omega-3 fatty acids may increase the anticoagulant activities of Fondaparinux. Heparin Omega-3 fatty acids may increase the anticoagulant activities of Heparin. Ibrutinib Omega-3 fatty acids may increase the antiplatelet activities of Ibrutinib. Icosapent ethyl Omega-3 fatty acids may increas...
Antithrombin is the most important physiological inhibitor of the various activated serine protease clotting factors, particularly thrombin. In vitro, the inhibition of thrombin by antithrombin is very slow; but greatly enhanced by heparin and related glycosaminoglycans. When a serine protease interacts wit...
In hemorrhagic shock, 10 mg per kg of heparin are harmful. Multiple microemboli are certainly not the only factor in irreversible hemorrhagic shock. However, prevention of thrombosis will increase the survival rate.B Bit-Alkhas Irani... BA Irani,EE Cliffton - 《Angiology》 被引量: 5发表: ...
HUVECs were purchased from the Qi Biological Center of Jiang Su, China. HUVECs were cultured in modified 1640 medium (Gibco-BRL, Gaithersburg, MD) containing 2 mM l-glutamine, 1.5 g/L sodium bicarbonate, 100 μg/mL heparin, 30 μg/mL EC growth supplement and 10% fetal bovine...
is reported to be required for efficient ACE2-dependent SARS-CoV-2 infection because heparin dramatically enhances the open conformation of SARS-CoV-2 RBD for ACE2 binding.121On RBD, the sulfate-binding site and ACE2-binding site are adjacent to each other to facilitate heparan sulfate-dependent...
The protective action of small doses of heparin (5 U./100 g) and the inefficiency of large doses (50 U./100 g) were shown. A dual role of mast cells in the disturbance mechanism of the vascular permeability in immobilization was established: damaging, at the expense of histamine and ...
Mechanism of action The theorized mechanism of action for quinine and related anti-malarial drugs is that these drugs are toxic to the malaria parasite. Specifically, the drugs interfere with the parasite's ability to break down and digest hemoglobin. Consequently, the parasite starves and/or buil...
Heparin The therapeutic efficacy of Heparin can be decreased when used in combination with Triamcinolone. Hepatitis A Vaccine The therapeutic efficacy of Hepatitis A Vaccine can be decreased when used in combination with Triamcinolone. Hepatitis B Vaccine (Recombinant) The therapeutic efficacy of Hepatitis...