1.1. Heparin and its mechanism of action as an anticoagulant Heparin, a vital anticoagulant, enhances the activity of endogenous inhibitors within the clotting cascade, thereby preserving blood fluidity (Ofosu and Gray, 1988). Its interaction with cellular components of the coagulation system exerts ...
The other important action of heparin is to release lipoprotein lipase from vascular wall, which splits chylomicron into non-esterified free fatty acid. Clinical method of heparin administration is divided into following three ways: (a) intravenous infusion of 25, 000 to 30, 000 units of ...
The subject of the invention is a method for analysing heparins or low-molecular-weight heparins, characterized in that the sample to be assayed is depolymerized by the action of heparinases and then, where appropriate, the depolymerizate obtained is reduced and then an analysis is carried ...
Objective To explore thrombolysis action of low molecular weight heparin ( LMWH ). 目的探讨低分子肝素 ( LMWH ) 的溶栓作用. 互联网 OBJECTIVE To establish a method for control endotoxin in Heparin sodium injection. 目的建立肝素钠注射液中细菌内毒素的检查方法. 互联网 Conclusion We treated corticosteroi...
Mechanism Of Action Heparin interacts with the naturally occurring plasma protein, Antithrombin III, to induce a conformational change, which markedly enhances theserineproteaseactivity of Antithrombin III, thereby inhibiting the activated coagulation factors involved in the clotting sequence, particularly Xa ...
12.1 Mechanism of Action Heparin interacts with the naturally occurring plasma protein, Antithrombin III, to induce a conformational change, which markedly enhances the serine protease activity of Antithrombin III, thereby inhibiting the activated coagulation factors involved in the clotting sequence, particu...
From my previous report it is supposed that the anticoagulant action of the peanut extract is skin to that of heparin. So I prepared heparin from dog's livers after the method originated by Charles-Scott, and investigated on this action ... 玉尾,延忠 - 《岡山医学会雑誌》 被引量: 0发表...
Action of heparin on the venom of Echis carinatus. AHUJA et al.have presented experimental evidence to show that heparin is capable of neutralizing the blood-coagulant action of Russell's viper venom in vit... AHUJA, M. L,VEERARAGHAVAN, N,MENON, I. G. K - 《Nature》 被引量: 29发表:...
the current most promising clinical technology for heparin conjugation involves incorporation of a single end point binding of heparin to grafts providing heparin with steric flexibility; this in turn facilitates heparin interaction with antithrombin III which minimizes its loss of anticoagulation action. Ca...
Role of heparin in the inactivation of thrombin, factor Xa, and plasmin by antithrombin III To characterize the mode of action of heparin, the kinetic behaviour of the inhibition of thrombin, factor Xa, and plasmin by antithrombin III was studied in the presence and absence of heparin. ...