Pharmacokinetics of M118, unfractionated heparin and enoxaparin sodium in normal and 5/6 nephrectomized uremic ratsOximesReactivators of cholinesteraseOrganophosphatesSomanTabunBiological markersPanaxydol, a polyacetylene compound isolated from Panaxginseng, exerts anti-proliferative effects against malignant cells....
This review focuses on pharmacologic information relevant to the dosing of unfractionated heparin, low molecular weight heparin, warfarin, bivalirudin, argatroban and fondaparinux in paediatric patients. The bulk of clinical experience with paediatric anticoagulation rests with the first three of these ...
The present investigation determined the molecular structure and the pharmacokinetic and pharmacodynamic profiles of oral unfractionated heparin containing... SA Mousa,F Zhang,A Aljada,... - 《Journal of Clinical Pharmacology》 被引量: 65发表: 2008年 Biopharmaceutics, pharmacokinetics and pharmacodynamics...
Traditionally, unfractionated heparin (UFH) and low molecular-weight heparin (LMWHs) have been utilised as the primary anticoagulant during cardiac surgery. However, both UFH and LMWHs have inherent limitations, often with potentially deleterious clinical conse- quences, such as heparin-induced ...
pharmacodynamicspharmacokineticstherapeutic usetolerabilityBackground: Enoxaparin was superior to unfractionated heparin (UFH), regardless of fibrinolytic agent in ST... RR Giraldez,SD Wiviott,JC Nicolau,... - 《Drugs》 被引量: 34发表: 2009年 Pharmacokinetics and Pharmacodynamics of Lanoteplase (n-PA...
Heparin binds reversibly to its target sites of action, antithrombin and the other serine proteases involved in coagulation, especially activated factor X.
Büller HR, Davidson BL, Decousus H, et al. Subcutaneous fondaparinux versus intravenous unfractionated heparin in the initial treatment of pulmonary embolism. N Engl J Med 2003 Oct 30; 349(18): 1695–702 PubMedGoogle Scholar The Fifth Organization to Assess Strategies in Acute Ischemic Syndromes...
Since the early nineties it has been shown that low molecular weight heparin (LMWH) has significant advantages over unfractionated heparin and oral anticoagulants for both the treatment and the prevention of thrombosis, not only in adults, but also in children. The present review was based on an...
Pharmacokinetics and pharmacodynamics of a therapeutic dose of unfractionated heparin (200 U/kg) administered subcutaneously or intravenously to healthy dogs. Vet Clin Pathol 2005;34:237-242.Diquelou A, Barbaste C, Gabaig AM, et al. Pharmacokinetics and pharmaco- dynamics of a therapeutic dose ...
Pharmacoki- netics of low-molecular-weight heparin and unfractionated heparin during elective aortobifemoral bypass grafting. J VASCSURGI991;14:208-i4.Kroneman H, Eikelboom BC, Knot EA, et al. (1991) Pharmacokinetics of low-molecular-weight heparin and unfractionated heparin during elective aortobi...