Systematic analyses of GWAS summary statistics from UK Biobank identified novel susceptibility loci and genes for upper gastrointestinal diseasesIn recent decades, upper gastrointestinal (GI) diseases have been highly prevalent worldwide. Although genome-wide association studies (GWASs) have identified ...
Summary statistics identified where low confidence filter was mis-applied Issue details here List of files affected (111 files): (GWAS_list_low_confidence_filter_update.txt.gz)[https://github.com/Nealelab/UK_Biobank_GWAS/blob/master/GWAS_list_low_confidence_filter_update.txt.gz] Of these 111 ...
data-importdata-extractionreproducibilityukbiobank UpdatedSep 18, 2024 R rivas-lab/ukbb-tools Star7 Code Issues Pull requests Tools for preprocessing, QC, and preliminary analyses from raw UK BioBank data gwasphewasukbiobankgrmgwas-summary-statisticsld-score-regressionphenotyping-algorithmsglobal-biobank-eng...
computational costs. This research has been conducted using the UK Biobank Resource under project 788. The work was funded by the Roslin Institute Strategic Programme Grant from the BBSRC (BB/P013732/1) and MRC grant (MR/N003179/1) granted to A.T. A.T. also acknowledges funding from the...
Methods: We built a disease–disease network (DDN) using UK Biobank (UKBB) summary data from a phenome-wide association study (PheWAS) to elaborate multiple disease associations. We also constructed egocentric DDNs, where each network focuses on a pregnancy-related disorder and its neighboring ...
With the re-release of UK Biobank genotype imputation (which we term imputed-v3), we have generated an updated set of GWAS summary statistics for the genetics community. Increased the number of phenotypes with application UKB31063 and addtl. custom curated phenotypes (see imputed-v3 Phenotypes)...
through a rigorous two-sample Mendelian randomization (MR) analysis. Methods: Genetic instrumental variables representing coagulation factors were sourced from four distinct data repositories. Summary statistics pertaining to ovarian cancer were obtained from two extensive Genome-Wide Association Studies (GWAS...
Two-sample Mendelian randomization methods were applied to the summary statistics of a genome-wide association study (GWAS) for self-reported facial aging from 417, 772 participants of the UK Biobank data. Twenty single-nucleotide ... Y Zhan,S Hgg - 《Geroscience》 被引量: 0发表: 2020年 加...
NHS Health Check attendance is associated with reduced multiorgan disease risk: a matched cohort study in the UK Biobank Celeste McCracken, Zahra Raisi-Estabragh, Liliana Szabo, John Robson, Betty Raman, Anya Topiwala, Adriana Roca-Fernández, Masud Husain, Steffen E. Petersen, Stefa...
This research has been conducted using the UK Biobank Resource under application number 16549. We would like to thank the participants and researchers from UK Biobank who significantly contributed or collected data. We thank the GABRIEL consortium and the EAGLE consortium for providing GWAS summary s...