bioinformaticsgwasukbiobankmulti-phenotype-imputation UpdatedMar 4, 2025 rmgpanw/codemapper Star3 R package for working with clinical codes rpackageukbiobank UpdatedFeb 26, 2025 R ivychad/Physical-Activity-BrainAGE Star1 Code Issues Pull requests ...
Tools for preprocessing, QC, and preliminary analyses from raw UK BioBank data gwasphewasukbiobankgrmgwas-summary-statisticsld-score-regressionphenotyping-algorithmsglobal-biobank-engine UpdatedAug 5, 2022 Jupyter Notebook Data management helper code for the UK Biobank. ...
UKB英国生物GWAS数据库入门指南 .英国生物库演示用户指南:入门 1 简介 英国生物库拥有2006年至2010年间在英国招募的50万40-69岁参与者(男女人数大致相等)的前所未有的数据。展示(可在http://www.ukbiobank.ac.uk)旨在以全面简洁的方式提供可用于健康相关研究的...
大家好,有小伙伴问Lee Lab处理的UK biobank的GWAS数据怎么寻找和下载,今天粗略讲一下。 首先,进入到官网,链接: https://www.leelabsg.org/resources。长这样: UK biobank的二分类GWAS数据(即疾病)点击链接…
研究剂量依赖性与疾病风险的关联确实是一个好思路,值得借鉴哦~~该研究采用了UKBB数据库数据,从UKBB数据库和GLGC数据库的GWAS数据中提取了3个作为暴露的遗传因子,并生成了遗传风险评分。先后进行了线性和非线性MR分析。采用比率法计算线性MR估计值,使用逻辑回归和Cox比例风险回归获得了暴露与主要结果的关联。应用分数阶...
TranscriptomeMethylationData was used from the GWAS Catalogue and validated in the UK Biobank cohort.Eight SNPs corresponding to six protein coding genes were highly associated with depression.The gene list includesTNXB, NCAM1, LTBP3, BTN3A2, DAG1 and FHIT.A genetic risk score specific for ...
今天学习下如何下载UKBiobank的数据并进行整理,把它变成TwoSampleMR能够使用的格式。 数据下载 打开ukbiobank的官网:https://www.nealelab.is/uk-biobank 打开后往下拉,找到results can be found here,点击它: 点击之后即可来到数据界面,首先是README这个sheet,这里会有一些介绍,每个文件包含哪些内容,每个文件的列名是...
UK Biobank在不久之前(2024年6月14日)突然暂停了AMS中的数据下载系统,当时未对具体原因和细节说明。 与博主之前预料的情况一致,UK Biobank Community今天宣布:UKB…阅读全文 赞同9 15 条评论 分享收藏 Lee Lab处理的UK biobank的疾病性状GWAS数据批量下载 旅行的白山茶 大家好,有小伙伴问...
The two-sample MR method requires minimal sample overlap between the exposure and outcome GWAS88; therefore, mental illness summary-level data were obtained mainly from the PGC, excluding UK Biobank participants. The GWAS of the mental illness traits considered were provided and analysed as case/...
With the re-release of UK Biobank genotype imputation (which we term imputed-v3), we have generated an updated set of GWAS summary statistics for the genetics community. Increased the number of phenotypes with application UKB31063 and addtl. custom curated phenotypes (see imputed-v3 Phenotypes)...