regulatory T cellsIt was long believed that epidermal Langerhans cells (LC) are responsible for the initiation of cellular immunity. Only recently it has been shown that in skin alone 5 different subtypes of dendritic cells (DC) can be identified. Among these, LC, but also two Langerin-...
The spatiotemporal regulation of immune cells in lymph nodes (LNs) is crucial for mounting protective T-cell responses, which are orchestrated by dendritic cells (DCs). However, it is unclear how the DC subsets are altered by the inflammatory milieu of LNs. Here, we show that the inflamed ...
The resulting cell type space still possessed several transcriptionally similar cell types (for example, various intestinal enterocytes, T cells or dendritic cells), which, left unaddressed, would reduce the linear independence of the basis matrix column space and, hence, would affect nu-SVR ...
Innate recognition of infection in vertebrates can lead to the induction of adaptive immune responses through activation of dendritic cells (DCs). DCs are ... RE Sousa - 《Current Opinion in Immunology》 被引量: 705发表: 2004年 Mast cells in allergy and infection: Versatile effector and regulat...
expression of CD23, CD35 and CD54 but no association with clinical outcomeAims: Follicular dendritic cells (FDC) are specialized antigen-presenting cells found exclusively in the germinal centre (GC), which can be detected in B cell non-Hodgkin lymphomas (NHL) as reactive bystander cells. Recen...
Dendritic cells (DCs) are mononuclear phagocytes that are specialized in the induction and functional polarization of effector lymphocytes, thus orchestrating immune defenses against infections and cancer. The population of DC encompasses distinct cell types that vary in their efficacy for complementary fun...
Dendritic cells (DC), present in the skin, are the first target cells of dengue virus (DENV). Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) is present on DC and recognizes N-glycosylation sites on the E-glycoprotein of DENV. Thus, the DC-SIGN/E...
Myeloid cells include basophils, dendritic cells, eosinophils, erythrocytes, macrophages, megakaryocytes, monocytes, neutrophils, and platelets, while lymphoid cells include B cells, T cells, and natural kills cells. 5. Unipotent Stem Cells Finally, we have the unipotent stem cells, which are the ...
[70]. Furthermore, it has been shown that particularLactobacillusspecies induced critical inflammatory cytokines and induced activation and maturation of dendritic cells [71]. It has also been shown that immature DCs efficiently captureLactobacillusspecies, and these bacteria activated human DCs, ...
This paper describes human lymph node fibroblast subsets at single-cell resolution and defines interactions of dendritic cells and GREM1+ FDCs in T cell zones, which are required for proper T cell function. Article CAS PubMed Google Scholar Fletcher, A. L. et al. Lymph node fibroblastic ...