Type II Secretion System Type II secretion systems(T2SS) enable bacteria to translocate proteins into the extracellular environment[63,64].L. pneumophilatransports more than 25 protein substrates through the T2SS[65]. The T2SS consists of a homologue of thePseudomonas aeruginosaprepilinpeptidasePilD,...
Type II secretion system: a magic beanstalk or a protein escalator. Biochimica et Biophysica Acta—Molecular Cell Research . 2014; 1843 (8):1568–1577. doi: 10.1016/j.bbamcr.2013.12.020. [ Cross Ref ]Nivaskumar M, Francetic O. Type II secretion system: a magic beanstalk or a protein ...
The type II secretion system: biogenesis, molecular architecture and mechanism Many gram-negative bacteria use the sophisticated type II secretion system (T2SS) to translocate a wide range of proteins from the periplasm across the out... KV Korotkov,M Sandkvist,WGJ Hol - 《Nature Reviews Microb...
The type 2 secretion system (T2SS) is present in some Gram-negative eubacteria and used to secrete proteins across the outer membrane. Here we report that certain representative heteroloboseans, jakobids, malawimonads and hemimastigotes unexpectedly possess homologues of core T2SS components. We ...
Secretin is a large outer-membrane channel found in secretion systems of Gram-negative bacteria, facilitating the last step for transfer of proteins into the extracellular environment. In the type II secretion system, a lipoprotein called pilotin is essential to bind and target its corresponding secr...
Type II secretion systems promote secretion of folded periplasmic proteins.These systems play important roles in bacterial adaptation and biopolymer recycling.The mechanisms of type II secretion and type IV pilus assembly are closely related.The molecular basis of exoprotein substrate selection is poorly ...
相反,有人建议将T4CP放置在T4SS的入口处,将底物直接转移到T4SS。已经提出了针对ssDNA底物的三种可能的转移途径:(i)通过T4CP六聚体的通道转移至T4SS;(ii)在其被T4CP摄取后,底物可以通过VirB4六聚体并从那里转移到T4SS;或(iii)在与ATP酶相互作用后,底物可直接通过IMC亚基形成的通道转移。
SummaryThe type II secretion system is a multi-protein complex that spans the cell envelope of Gram-negative bacteria and promotes the secretion of protein... MD Gray,M Bagdasarian,WGJ Hol,... - 《Molecular Microbiology》 被引量: 89发表: 2011年 Proteomic analysis of Vibrio cholerae outer memb...
LT secretion requires a functional type II secretion system Secretion of LT fromETECrequires the presence of a functionaltype II secretion system(seeChapter 13), similar to the secretion apparatus for CT inVibrio cholerae(Tauschek et al., 2002). In the protypical ETEC strainH10407, LT secr...
Type IX secretion system (T9SS), exclusively present in the Bacteroidetes phylum, has been studied mainly in Flavobacterium johnsoniae and Porphyromonas gingivalis. Among the 18 genes, essential for T9SS function, a group of four, porK-N (P. gingiva