Women with insulin resistance are prone to develop gestational diabetes during pregnancy and both men and women who have insulin resistance can progress to type 2 diabetes primarily prompted by age, increased body weight, and decreased physical activity....
Insulin Resistance and Type 2 DiabetesFor well over half a century, the link between in-sulin resistance and type 2 diabetes has been recognized. Insulin resistance is important. Not only is it the most powerful predictor of future development of type 2 diabetes, it is also a therapeutic ...
Insulin resistance, type 2 diabetes and chronic liver disease. A deadly trio. Clinical Medicine: Endocrinology and Diabetes 2009: 281-88.Insulin Resistance,Type 2 Diabetes and Chronic Liver Disease.A Deadly Trio. LonardoA,Loriap. Clinical Medicine Insights Endocrinology&Diabetes . 2012...
Type 2diabetesis the most common type of diabetes. It is a chronic condition in which blood glucose (sugar) can no longer be regulated. There are two reasons for this. First, the cells of the body become resistant toinsulin(insulin resistant). Insulin works like a key to let glucose (bl...
Ethnic variation in insulin resistance and risk of type 2 diabetes. In: Reaven G, Laws A, editors. Insulin Resistance: The Metabolic Syndrome X. Humana Press; Totowa, NJ: 1999. pp. 19–34.P.M. McKeigue, Ethnic variations in insulin resistance and risk of type 2 diabetes, in: G.M....
Insulin resistance is a core feature of type 2 diabetes mellitus (T2DM) and contributes not only to the hyperglycaemia that defines diabetes mellitus but also to the hyperlipidaemia, inflammation, oxidative stress and atherosclerosis that accompany it T2DM substantially increases risk of not only cerebro...
Alzheimer disease (AD) and related dementias share numerous mechanistic and epidemiological similarities with type 2 diabetes mellitus (T2DM). However, whether these associations result from synergistic interactions between the disorders is unclear. This
82Altmetric Metrics Abstract Obesity is associated with an increased risk of developing insulin resistance and type 2 diabetes. In obese individuals, adipose tissue releases increased amounts of non-esterified fatty acids, glycerol, hormones, pro-inflammatory cytokines and other factors that are involved...
Insulin resistance and B-cell dysfunction are two main components in the pathogenesis of type 2 diabetes,and insulin resistance is initial factor.It has been found that abnormal signaling protein and inflammatory factor are closely related with insulin resistance.Investigating the relationship between them...
High levels of free fatty acids have emerged as a major link between obesity and insulin resistance/Type 2 diabetes. In pancreatic β cells, free fatty acids potentiate glucose-stimulated insulin secretion precisely to the extent needed to compensate for the free fatty acid-induced insulin resistance...