Insulin resistance is defined as the impaired sensitivity of tissues, mainly skeletal muscle, liver, and adipose tissues, to the action of insulin. Insulin resistance precedes 尾-cell dysfunction and plays a key role in the development of type 2 diabetes. After carbohydrate ingestion, insulin ...
2) diabetes and insulin resistance 糖尿病与胰岛素抵抗 1. There is new understanding of certain traditional risk factors such as hypertension,unusual blood fats,diabetes and insulin resistance. 多种危险因素共同作用导致了冠心病的发生,对确认的某些传统危险因素高血压、血脂异常、糖尿病与胰岛素抵抗有了新...
Type 2 diabetes (T2D) typically starts with insulin resistance in peripheral tissues and proceeds with gradual loss of islet function due to the reduction in β-cell mass or dedifferentiation of β cells1,2. More than 30% of T2D patients eventually rely on exogenous insulin treatment. Cadaveric ...
Type 2 diabetes is a disease that affects how your child's body uses glucose (sugar). Type 2 diabetes develops because either the body cannot make enough insulin, or it cannot use the insulin correctly. You can help your child manage diabetes with healthy nutrition and physical activity ...
Considerable overlap has been identified in the risk factors, comorbidities and putative pathophysiological mechanisms of Alzheimer disease and related dementias (ADRDs) and type 2 diabetes mellitus (T2DM), two of the most pressing epidemics of our time. Much is known about the biology of each cond...
Type II diabetes, also called non-insulin-dependent diabetes mellitus (NIDDM), is characterized by high blood glucose resulting from the genetic defect of the GLUT4 genome. The latter is manifested in the diminished glucose uptake into skeletal muscles. In normal human beings, insulin combines with...
Genetic variations leading to the altered production or function of circulating innate immune proteins, cellular pattern recognition receptors and inflammatory cytokines are linked to obesity, insulin resistance and type 2 diabetes. Components of the innate immune system in the muscle, bone, liver and ...
Type 2diabetesis the most common type of diabetes. It is a chronic condition in which blood glucose (sugar) can no longer be regulated. There are two reasons for this. First, the cells of the body become resistant toinsulin(insulin resistant). Insulin works like a key to let glucose (bl...
Protein Biomarkers for Insulin Resistance and Type 2 Diabetes Risk in Two Large Community Cohorts. Insulin resistance (IR) is a precursor of type 2 diabetes (T2D), and improved risk prediction and understanding of the pathogenesis are needed. We used a n... Christoph,Nowak,Johan,... - 《Di...
EBSCO care.diabetesjournals.org (全网免费下载) 相似文献 参考文献 引证文献Insulin resistance, impaired early insulin response, and insulin propeptides as predictors of the development of type 2 diabetes: a population-based, 7-yea... 'Insulin resistance, impaired early insulin response, and insulin ...