Insulin Resistance vs Diabetes Insulin resistance and diabetes have come into the day to day vocabulary in recent years because of the sheer number of people who suffer due to elevated levels of blood sugar. World Health Organization has declared diabetes as the biggest pandemic to sweep the earth...
If you have type 1, your body doesn't make enough insulin. Withtype 2 diabetes, your body can make insulin but can't use it well. The cells in your muscles, fat, and liver build up what's called insulin resistance. With type 1 diabetes, you need to use man-made insulin every day ...
Insulin resistance and hypertension in patients with type 1 diabetes. J Diabetes Complications. 2011;25(4):232-6.Chillaro´ n JJ, Sales MP, Flores-Le-Roux JA, et al. Insulin resistance and hyper- tension in patients with type 1 diabetes. J Diabet Complications 2011;25(July- August (4...
Metabolic liver disease is highly prevalent in subjects with obesity and involves inflammation, insulin resistance, and fibrosis, leading to cirrhosis. Here, the authors show the IFNγ-IL12 axis in regulating intercellular crosstalk in the liver and playing a major role in the pathogenesis of metabo...
Insulin resistance typically remains undetected and consequently is also understudied. Collect- ing detailed clinical information allowed us to control for potential confounders. The fact that the results remained consistent in subgroup analyses or when we controlled for relevant clinical, treatment, or ...
Type 2 diabetes is characterized by insulin resistance and progressive loss of β-cell insulin secretion.6 In contrast, type 1 diabetes is the result of autoimmune β-cell destruction, usually leading to absolute insulin deficiency. Prediabetes is the term used for individuals whose blood glucose ...
Replacing saturated fats with polyunsaturated fats results in reductions of HbA1c, fasting glucose concentration and liver fat content and improved Homeostatic Model Assessment of insulin resistance (HOMA-IR) [107]. Replacement with monounsaturated fats from primarily vegetable sources is also associated ...
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes have been debated extensively. The con
To evaluate the mechanism of insulin resistance in type 1 diabetes mellitus, we measured insulin sensitivity in vivo and insulin action in adipocytes in vitro. The study groups consisted of 18 insulin-treated type 1 diabetic patients and 14 matched normal subjects. In each subject, insulin-mediated...
Interactions among hepatic inflammation and fibrosis, atherogenic dyslipidemia, insulin resistance induced by hepatic fat accumulation9,10, and systemic release of pro-inflammatory cytokines11 and hepatokines such as fetuin A, fetuin B, selenoprotein, and fibroblast growth factor 2112,13 are involved in...